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Details

Stereochemistry ACHIRAL
Molecular Formula C3H7NS
Molecular Weight 89.159
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THIAZOLIDINE

SMILES

C1CSCN1

InChI

InChIKey=OGYGFUAIIOPWQD-UHFFFAOYSA-N
InChI=1S/C3H7NS/c1-2-5-3-4-1/h4H,1-3H2

HIDE SMILES / InChI

Molecular Formula C3H7NS
Molecular Weight 89.159
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones.
2009-05
The effects of Thiazolidinediones on metabolic complications and Lipodystrophy in HIV-infected patients.
2009
Comparative metabolism and pharmacokinetics of seven neonicotinoid insecticides in spinach.
2008-11-12
Are the adverse effects of glitazones linked to induced testosterone deficiency?
2008-10-15
NMR and theoretical calculations: a unified view of the cis/trans isomerization of 2-substituted thiazolidines containing peptides.
2008-08-14
Acarbose treatment increases serum total adiponectin levels in patients with type 2 diabetes.
2008-07
Design, synthesis and evaluation of potent thymidylate synthase X inhibitors.
2008-06-15
Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma.
2008-06-01
Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process.
2008-05-21
Controlling orientations of immobilized oligopeptides using N-terminal cysteine labels.
2008-05-20
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents.
2008-03
Semisynthetic analogues of PSC-RANTES, a potent anti-HIV protein.
2008-02
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae.
2008-01-07
Role of Peoxisome Proliferator Activator Receptor gamma on Blood Retinal Barrier Breakdown.
2008
Impact of the socioeconomic status on the probability of receiving formulary restricted thiazolidine (TZDs).
2008
Conformational preferences of pseudoproline residues.
2007-11-01
Lipids behavior and adverse effects for oral antidiabetic agents in patients with Type 2 diabetes treated with sulfonylureas alone based on systematic review.
2007-10
3D-QSAR studies of Dipeptidyl peptidase IV inhibitors using a docking based alignment.
2007-10
Reversal of systemic hypertension-associated cardiac remodeling in chronic pressure overload myocardium by ciglitazone.
2007-09-07
Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes.
2007-08-15
Synthesis and antiproliferative activity of thiazolidine analogs for melanoma.
2007-08-01
Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones.
2007-07
Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore.
2007-02-07
Conformational stability of Abeta-(25-35) in the presence of thiazolidine derivatives.
2007-02
Design, synthesis and antibacterial activity of novel 1,3-thiazolidine pyrimidine nucleoside analogues.
2006-11-15
Determination of glyoxylyl-peptide concentration using oxime chemistry and RP-HPLC analysis.
2006-11
Direct trapping of formaldehyde formed via oxidative N-demethylation of N,N-dialkylarylamines by Bacillus megaterium using cysteamine derivatization.
2006-11
Ring opening and expansion of aziridines in a silica-water reaction medium.
2006-09-15
[Analysis of variant and modified structures of proteins by mass spectrometry--application for clinical laboratory test].
2006-09
Purification and characterization of a novel L-2-amino-Delta2-thiazoline-4-carboxylic acid hydrolase from Pseudomonas sp. strain ON-4a expressed in E. coli.
2006-09
Enhanced bioavailability of a new thiazolidine derivative FPFS-410, an antidiabetic and lipid-lowering drug, after oral administration of its hydroxypropyl-beta-cyclodextrin complex to bile duct-cannulated rats.
2006-08
[(S)-gamma-(Arylamino)prolyl]thiazolidine compounds as a novel series of potent and stable DPP-IV inhibitors.
2006-06-01
Conformational behavior of dimethyl 5-methyl-1H,3H-pyrrolo[1,2-c][1,3]thiazole-6,7-dicarboxylate 2,2-dioxide isolated in low-temperature matrixes.
2006-05-25
Stabilization of the biologically active conformation of the principal neutralizing determinant of HIV-1(IIIB) containing a cis-proline surrogate: 1H NMR and molecular modeling study.
2006-04-04
Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound.
2006-03-01
A study of anti-inflammatory activity of some novel alpha-amino naphthalene and beta-amino naphthalene derivatives.
2006-03
Improvement of solubility and oral bioavailability of 2-(N-cyanoimino)-5-[(E)-4-styrylbenzylidene]-4-oxothiazolidine (FPFS-410) with antidiabetic and lipid-lowering activities in dogs by 2-hydroxypropyl-beta-cyclodextrin.
2006-03
Development of a compound-specific carbon isotope analysis method for atmospheric formaldehyde via NaHSO3 and cysteamine derivatization.
2006-02-15
An automated peptide and protein thiazolidine coupling chemistry for biosensor immobilization giving a unique N-terminal orientation.
2006-01-15
Alpha-thiolamines such as cysteine and cysteamine act as effective transglycating agents due to formation of irreversible thiazolidine derivatives.
2006
Chemical synthesis of proteins and circular peptides using Nalpha-(1-phenyl-2-mercaptoethyl) auxiliaries.
2005-11
JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
2005-10
Protein splicing: its discovery and structural insight into novel chemical mechanisms.
2005-08
Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
2005-07-15
Synthesis and evaluation of 3-(carboxymethylidene)- and 3-(carboxymethyl)penicillinates as inhibitors of beta-lactamase.
2005-05-27
Use of carbonyl group addition--elimination reactions for synthesis of nucleic acid conjugates.
2005-05-19
2-(Acridin-9-ylimino)-3-dimethylamino-1,3-thiazolidin-4-one.
2005-04
Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A beta-lactamase with benzylpenicillin.
2005-03-30
Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier.
2004-11-16
Specific determination of cysteine and penicillamine through cyclization to 2-thioxothiazolidine-4-carboxylic acids.
2002-03-11
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:56:04 GMT 2025
Edited
by admin
on Mon Mar 31 19:56:04 GMT 2025
Record UNII
I320806BKW
Record Status Validated (UNII)
Record Version
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Name Type Language
THIAZOLIDINE
Systematic Name English
1,3-THIAZOLIDINE
Preferred Name English
TETRAHYDROTHIAZOLE
Systematic Name English
NSC-357911
Code English
Code System Code Type Description
EPA CompTox
DTXSID10198447
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
SMS_ID
300000053977
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
NSC
357911
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
CHEBI
50120
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
FDA UNII
I320806BKW
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
PUBCHEM
10444
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
CAS
504-78-9
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
CHEBI
35622
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
ECHA (EC/EINECS)
208-002-5
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
PRIMARY
WIKIPEDIA
THIAZOLIDINE
Created by admin on Mon Mar 31 19:56:04 GMT 2025 , Edited by admin on Mon Mar 31 19:56:04 GMT 2025
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