DOCARAVIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 05:39:25 GMT 2025` Edited by `admin` on `Wed Apr 02 05:39:25 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	MOUSE
Sequence Type	COMPLETE
Record UNII	I0HK032RR6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DOCARAVIMAB

Official Name

English

62-71-3

Preferred Name

English

Docaravimab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G2B-KAPPA, ANTI-(RABIES VIRUS STRAINERA (EVELYN-ROCKITNIKI-ABELSETH) GLYCOPROTEIN ECTODOMAIN EPITOPE G-III), MUS MUSCULUS MONOCLONAL ANTIBODY

Common Name

English

IMMUNOGLOBULIN G2B, ANTI-(RABIES VIRUS STRAIN EVELYN-ROCKITNIKI-ABELSETH GLYCOPROTEIN ECTODOMAIN EPITOPE G-III) (MUS MUSCULUS MONOCLONAL 62-71-3 .GAMMA.2B-CHAIN), DISULFIDE WITH MUS MUSCULUS MONOCLONAL 62-71-3 .KAPPA.-CHAIN, DIMER

Common Name

English

IMMUNOGLOBULIN G2, ANTI-(RABIES VIRUS STRAIN EVELYN-ROCKITNIKI-ABELSETH GLYCOPROTEIN ECTODOMAIN EPITOPE G-III) (MUS MUSCULUS MONOCLONAL .GAMMA.2-CHAIN), DISULFIDE WITH MUS MUSCULUS MONOCLONAL .KAPPA.-CHAIN, DIMER

Common Name

English

docaravimab [INN]

Common Name

English

Code System Code Type Description

INN

11198

Created by admin on Wed Apr 02 05:39:25 GMT 2025 , Edited by admin on Wed Apr 02 05:39:25 GMT 2025

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SMS_ID

300000023636

Created by admin on Wed Apr 02 05:39:25 GMT 2025 , Edited by admin on Wed Apr 02 05:39:25 GMT 2025

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FDA UNII

I0HK032RR6

Created by admin on Wed Apr 02 05:39:25 GMT 2025 , Edited by admin on Wed Apr 02 05:39:25 GMT 2025

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NCI_THESAURUS

C175773

Created by admin on Wed Apr 02 05:39:25 GMT 2025 , Edited by admin on Wed Apr 02 05:39:25 GMT 2025

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CAS

2247196-23-0

Created by admin on Wed Apr 02 05:39:25 GMT 2025 , Edited by admin on Wed Apr 02 05:39:25 GMT 2025

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From	To
1_22	1_95
1_375	1_433
2_22	2_95
2_134	4_214
2_146	2_201
1_134	3_214
2_269	2_329
2_375	2_433
3_23	3_88
3_134	3_194
1_146	1_201
4_23	4_88
4_134	4_194
1_228	2_228
1_231	2_231
1_234	2_234
1_237	2_237
1_269	1_329

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_305
N	2_305

Related Record Type Details


					XVG2C8B79L

RABIES VIRUS STRAIN EVELYN-ROKITNICKI-ABELSETH

TARGET -> INHIBITOR

Related Record Type Details


					I0HK032RR6

ACTIVE MOIETY

Comments:

Binds to site III on G-protein of rabies virus envelope

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_455] [2_455]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL