FUROBUFEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12O4
Molecular Weight	268.2641
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CCC(=O)C1=CC2=C(OC3=C2C=CC=C3)C=C1

InChI

InChIKey=LQVMQEYROPXMQH-UHFFFAOYSA-N

InChI=1S/C16H12O4/c17-13(6-8-16(18)19)10-5-7-15-12(9-10)11-3-1-2-4-14(11)20-15/h1-5,7,9H,6,8H2,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C16H12O4
Molecular Weight	268.2641
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4850589

Furobufen, a propionic acid derivative produced anti-inflammatory, antiarthritic, and antipyretic effects. It was shown that this compound could reduce the pain resulting from an acute inflammatory reaction and the activity profile of furobufen was similar to that of the non-steroidal anti-inflammatory drugs. Information about the current development of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Disposition of etodolac, other anti-inflammatory pyranoindole-1-acetic acids and furobufen in normal and adjuvant arthritic rats.	1982-02	6460096
Disposition of furobufen in mice, rats, dogs, and man.	1981-03-01	6113109
Anti-inflammatory properties of furobufen.	1974-06	4850589

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:52:00 GMT 2025` Edited by `admin` on `Mon Mar 31 17:52:00 GMT 2025`
Record UNII	HW206V7TUA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FUROBUFEN

Official Name

English

AY-21,367

Preferred Name

English

?-Oxo-2-dibenzofuranbutyric acid

Systematic Name

English

NSC-89140

Code

English

furobufen [INN]

Common Name

English

AY-21367

Code

English

FUROBUFEN [USAN]

Common Name

English

2-DIBENZOFURANBUTANOIC ACID, .GAMMA.-OXO-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257