TALERANOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H26O5
Molecular Weight	322.396
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H]1CCC[C@@H](O)CCCCCC2=C(C(O)=CC(O)=C2)C(=O)O1

InChI

InChIKey=DWTTZBARDOXEAM-JSGCOSHPSA-N

InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H26O5
Molecular Weight	322.396
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6351181

Taleranol (also known as P-1560) a weak estrogen and a minor metabolite and epimer of the drug, zeranol. Zeranol is an anabolic agent that used in animal feed and is intended for human consumption, is noncarcinogenic, nonteratogenic, and nonmutagenic.

Approval Year

PubMed

Title	Date	PubMed
Assessment of oestrogenic potency of chemicals used as growth promoter by in-vitro methods.	2001 May	11331656
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.	2003 Oct	14565775
Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different compounds with both receptor types.	2004 Jul	15276617
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities.	2012 Nov 19	23013281
Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassays.	2014 Dec	25455890
Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors.	2014 Oct 1	25106122
Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.	2015 Feb	25349334

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:35:18 GMT 2023` Edited by `admin` on `Fri Dec 15 16:35:18 GMT 2023`
Record UNII	HUN219N434
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TALERANOL

Official Name

English

(3S,7S)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one

Systematic Name

English

TALERANOL [USAN]

Common Name

English

taleranol [INN]

Common Name

English

P-1560

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C2182