TALERANOL

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H26O5
Molecular Weight	322.396
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

C[C@H]1CCC[C@@H](O)CCCCCC2=CC(O)=CC(O)=C2C(=O)O1

InChI

InChIKey=DWTTZBARDOXEAM-JSGCOSHPSA-N

InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H26O5
Molecular Weight	322.396
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description

Taleranol (also known as P-1560) a weak estrogen and a minor metabolite and epimer of the drug, zeranol. Zeranol is an anabolic agent that used in animal feed and is intended for human consumption, is noncarcinogenic, nonteratogenic, and nonmutagenic.

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.	2003 Oct	14565775
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.	2015 Feb	25349334

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Substance Class	Chemical
Record UNII	HUN219N434
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TALERANOL

Official Name

English

P-1560

Preferred Name

English

(3S,7S)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one

Systematic Name

English

TALERANOL [USAN]

Common Name

English

taleranol [INN]

Common Name

English

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Classification Tree

Code System

Code

Therapeutic Estrogen

NCI_THESAURUS

C2182

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Code System

Code

Type

Description

MESH

C028226

PRIMARY

FDA UNII

HUN219N434

PRIMARY

ChEMBL

CHEMBL491510

PRIMARY

EPA CompTox

DTXSID3022532

PRIMARY

WIKIPEDIA

Taleranol

PRIMARY

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Related Record

Type

Details


					5W827M159J

ZEARALENONE

PARENT -> METABOLITE

Amount:

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Related Record

Type

Details


					HUN219N434

TALERANOL

ACTIVE MOIETY

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SMILES

InChI

Description<div class="info-popup-container"><div><span class="pop-sub-key ">Sources:&nbsp;</span><span class="pop-sub-val"><span class="ext-link"><a target="_self" href="https://www.ncbi.nlm.nih.gov/pubmed/6351181">https://www.ncbi.nlm.nih.gov/pubmed/6351181</a></span></span></div></div>

Approval Year

PubMed

Description