Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H31NO11 |
| Molecular Weight | 545.5351 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2C(=O)C3=C(O)C4=C(C[C@](O)(C[C@@H]4O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)[C@@H](O)CO)C(O)=C3C(=O)C2=CC=C1
InChI
InChIKey=NKZRZOVSJNSBFR-FEMMEMONSA-N
InChI=1S/C27H31NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15-17,22,29-31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,16-,17-,22+,27-/m0/s1
| Molecular Formula | C27H31NO11 |
| Molecular Weight | 545.5351 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3. | 2015-06-05 |
|
| Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4'-amino-3,5-dihydroxy-trans-stilbene. | 2013 |
|
| Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin. | 2008-05 |
|
| Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy. | 2001-12-01 |
|
| The role of biotransformation in anthracycline-induced cardiotoxicity in mice. | 1993-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:12:55 GMT 2025
by
admin
on
Mon Mar 31 22:12:55 GMT 2025
|
| Record UNII |
HUH05KI4CF
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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HUH05KI4CF
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133817
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DTXSID70920620
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54193-28-1
Created by
admin on Mon Mar 31 22:12:55 GMT 2025 , Edited by admin on Mon Mar 31 22:12:55 GMT 2025
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83970
Created by
admin on Mon Mar 31 22:12:55 GMT 2025 , Edited by admin on Mon Mar 31 22:12:55 GMT 2025
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| Related Record | Type | Details | ||
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