HISTONE-LYSINE N-METHYLTRANSFERASE 2A

Approval Year

Substance Class	Protein
Protein Type	TRANSCRIPTION FACTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	HR355N7JYW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HISTONE-LYSINE N-METHYLTRANSFERASE 2A

Common Name

English

ALL-1

Preferred Name

English

MYELOID/LYMPHOID OR MIXED-LINEAGE LEUKEMIA

Common Name

English

MLL-1

Common Name

English

MLL1

Common Name

English

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Code System

Code

Type

Description

FDA UNII

HR355N7JYW

PRIMARY

UNIPROT

Q03164

PRIMARY

PHAROS

Q03164

PRIMARY

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Subunit 0

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Related Record

Type

Details


					VW83Y2JLZ5

Enzomenib

INHIBITOR OF PROTEIN-PROTEIN INTERACTION->TARGET

Amount:

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Structural Modifications

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Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1845] [1_2147] [1_2525] [1_3372]	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[1_239] [1_373] [1_636] [1_1130] [1_1235] [1_2958] [1_3462]	N6-ACETYLLYSINE	470AD5VY1X
AMINO_ACID_SUBSTITUTION	[1_136] [1_142] [1_197] [1_518] [1_680] [1_926] [1_1056] [1_1837] [1_1858] [1_2098] [1_2151] [1_2201] [1_2611] [1_2796] [1_2955] [1_3036] [1_3511] [1_3515] [1_3527]	DEXFOSFOSERINE	VI4F0K069V

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 431765.425 Da (average)
Molecular Formula	CHEMICAL	ESTIMATED C18614H30098O6021N5491S144

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