Retavibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 13:07:44 GMT 2025` Edited by `admin` on `Wed Apr 02 13:07:44 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	HQ9W597Z73
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Retavibart

Official Name

English

TNM-001

Preferred Name

English

retavibart [INN]

Common Name

English

TNM001

Code

English

immunoglobulin G1-kappa, anti-[human respiratory syncytial virus (RSV) fusion glycoprotein F], Homo sapiens monoclonal antibody (retavibart)

Common Name

English

Immunoglobulin G1 [438-leucine,444-serine], anti-(Respiratory syncytial virus pre-fusion F protein) (human monoclonal TNM001 ?1-chain), disulfide with human monoclonal TNM001 ?-chain, dimer

Common Name

English

H-gamma1 heavy chain Homo sapiens (1-457) [VH (Homo sapiens IGHV5-51*01 (86.7%) -(IGHD) -IGHJ2*01 (93.8%), CDR-IMGT [8.8.20] (26-33.51-58.97-116)) (1-127) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, 9-G1v24 CH3 L107, S114 (CH1 R120 (224)

Common Name

English

Code System Code Type Description

INN

13554

Created by admin on Wed Apr 02 13:07:44 GMT 2025 , Edited by admin on Wed Apr 02 13:07:44 GMT 2025

PRIMARY

CAS

3023741-03-6

Created by admin on Wed Apr 02 13:07:44 GMT 2025 , Edited by admin on Wed Apr 02 13:07:44 GMT 2025

PRIMARY

FDA UNII

HQ9W597Z73

Created by admin on Wed Apr 02 13:07:44 GMT 2025 , Edited by admin on Wed Apr 02 13:07:44 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_154	2_210
2_230	4_215
2_271	2_331
1_154	1_210
2_377	2_435
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_230	3_215
1_236	2_236
1_239	2_239
1_271	1_331
1_377	1_435

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_307
N	2_307

Related Record Type Details


					HQ9W597Z73

Retavibart

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_457] [2_457]	C-TERMINUS	K	Amount:	LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	Q	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL