U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:00:17 GMT 2023
Edited
by admin
on Sat Dec 16 14:00:17 GMT 2023
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Type COMPLETE
Record UNII
HOG226RYH1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EMERFETAMAB
USAN   INN  
Official Name English
EMERFETAMAB [USAN]
Common Name English
IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS CD33 (SIALIC ACID BINDING IG-LIKE LECTIN 3, SIGLEC3, SIGLEC-3, GP67, P67)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE CHAIN (SCFV)2-SCFC, BISPECIFIC; IG SCFV-SCFV-SCFC S
Common Name English
AMG-673
Code English
emerfetamab [INN]
Common Name English
IMMUNOGLOBULIN, ANTI-(HUMAN SIALIC ACID-BINDING IG-LIKE LECTIN 3) (HUMAN MONOCLONAL 1837MNGSSMABC SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSI
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 655818
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
Code System Code Type Description
CAS
2250261-27-7
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
PRIMARY
FDA UNII
HOG226RYH1
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
PRIMARY
USAN
JK-129
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
PRIMARY
CAS
2641417-67-4
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
NO STRUCTURE GIVEN
INN
11239
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
PRIMARY
NCI_THESAURUS
C175778
Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023
PRIMARY
From To
1_22 1_96
1_160 1_231
1_44 1_243
1_278 1_354
1_418 1_486
1_515 1_772
1_550 1_610
1_807 1_867
1_581 1_591
1_838 1_848
1_656 1_714
1_913 1_971
Related Record Type Details
TARGET -> INHIBITOR
CYTOXICITY
EC50
TARGET -> ACTIVATOR
BINDING
Kd
TARGET -> INHIBITOR
BINDING
Kd
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL