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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 21:58:02 GMT 2025
Edited
by admin
on Tue Apr 01 21:58:02 GMT 2025
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Type COMPLETE
Record UNII
HOG226RYH1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IMMUNOGLOBULIN, ANTI-(HUMAN SIALIC ACID-BINDING IG-LIKE LECTIN 3) (HUMAN MONOCLONAL 1837MNGSSMABC SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSI
Preferred Name English
EMERFETAMAB
USAN   INN  
Official Name English
EMERFETAMAB [USAN]
Common Name English
IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS CD33 (SIALIC ACID BINDING IG-LIKE LECTIN 3, SIGLEC3, SIGLEC-3, GP67, P67)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE CHAIN (SCFV)2-SCFC, BISPECIFIC; IG SCFV-SCFV-SCFC S
Common Name English
AMG-673
Code English
emerfetamab [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 655818
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
Code System Code Type Description
CAS
2250261-27-7
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
PRIMARY
FDA UNII
HOG226RYH1
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
PRIMARY
USAN
JK-129
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
PRIMARY
CAS
2641417-67-4
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
NO STRUCTURE GIVEN
INN
11239
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
PRIMARY
NCI_THESAURUS
C175778
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
PRIMARY
SMS_ID
300000035040
Created by admin on Tue Apr 01 21:58:02 GMT 2025 , Edited by admin on Tue Apr 01 21:58:02 GMT 2025
PRIMARY
From To
1_22 1_96
1_160 1_231
1_44 1_243
1_278 1_354
1_418 1_486
1_515 1_772
1_550 1_610
1_807 1_867
1_581 1_591
1_838 1_848
1_656 1_714
1_913 1_971
Related Record Type Details
MYELOID CELL SURFACE ANTIGEN CD33
TARGET -> INHIBITOR
CYTOXICITY
EC50
CD3
CD3
TARGET -> ACTIVATOR
BINDING
Kd
MYELOID CELL SURFACE ANTIGEN CD33
TARGET -> INHIBITOR
BINDING
Kd
Related Record Type Details
EMERFETAMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID REMOVAL [1_993] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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