EMERFETAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:00:17 GMT 2023` Edited by `admin` on `Sat Dec 16 14:00:17 GMT 2023`
Protein Type	FC FUSION PROTEIN
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	HOG226RYH1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EMERFETAMAB

Official Name

English

EMERFETAMAB [USAN]

Common Name

English

IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS CD33 (SIALIC ACID BINDING IG-LIKE LECTIN 3, SIGLEC3, SIGLEC-3, GP67, P67)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE CHAIN (SCFV)2-SCFC, BISPECIFIC; IG SCFV-SCFV-SCFC S

Common Name

English

AMG-673

Code

English

emerfetamab [INN]

Common Name

English

IMMUNOGLOBULIN, ANTI-(HUMAN SIALIC ACID-BINDING IG-LIKE LECTIN 3) (HUMAN MONOCLONAL 1837MNGSSMABC SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSI

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

655818

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

Code System Code Type Description

CAS

2250261-27-7

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

PRIMARY

FDA UNII

HOG226RYH1

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

PRIMARY

USAN

JK-129

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

PRIMARY

CAS

2641417-67-4

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

NO STRUCTURE GIVEN

INN

11239

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

PRIMARY

NCI_THESAURUS

C175778

Created by admin on Sat Dec 16 14:00:17 GMT 2023 , Edited by admin on Sat Dec 16 14:00:17 GMT 2023

PRIMARY

From	To
1_22	1_96
1_160	1_231
1_44	1_243
1_278	1_354
1_418	1_486
1_515	1_772
1_550	1_610
1_807	1_867
1_581	1_591
1_838	1_848
1_656	1_714
1_913	1_971

Related Record Type Details


					HX0GZ7OLW5

MYELOID CELL SURFACE ANTIGEN CD33

TARGET -> INHIBITOR

Interaction Type:

CYTOXICITY

Qualification:

EC50

Amount:


					ZLW14X2D30

CD3

TARGET -> ACTIVATOR

Interaction Type:

BINDING

Qualification:

Kd

Amount:


					HX0GZ7OLW5

MYELOID CELL SURFACE ANTIGEN CD33

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

Kd

Amount:

Related Record Type Details


					HOG226RYH1

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL