Varokibart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:07:47 GMT 2023` Edited by `admin` on `Sat Dec 16 15:07:47 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	HO08KW5LSB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Varokibart

Official Name

English

immunoglobulin G4-lambda, anti-[Homo sapiens IL5 (interleukin 5, IL-5)], Homo sapiens monoclonal antibody

Common Name

English

Immunoglobulin G4 [225-proline,249-tyrosine,251-threonine,253-glutamic acid,de-C-terminal-lysine], anti-(human interleukin 5) (human monoclonal TEV-53275 γ4-chain), disulfide with human monoclonal TEV-53275 λ-chain, dimer

Common Name

English

gamma4 heavy chain Homo sapiens (1-443) [VH (Homo sapiens IGHV4-31*02 (99%) -(IGHD) -IGHJ5*01 (93.8%)) [10.7.9](26-35.53-59.98-106) (1-117) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v21 CH2 Y15.1, T16, E18 (CH1 (118-215), hinge 1-12 S10>P (2

Common Name

English

TEV-53275

Code

English

Immunoglobulin G4 [225-proline,249-tyrosine,251-threonine,253-glutamic acid,de-444-lysine], anti-(human interleukin 5) (human clone 3A5.046 γ4-chain), disulfide with human clone 3A5.046 λ-chain, dimer

Common Name

English

varokibart [INN]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C190452

Created by admin on Sat Dec 16 15:07:47 GMT 2023 , Edited by admin on Sat Dec 16 15:07:47 GMT 2023

PRIMARY

INN

12309

Created by admin on Sat Dec 16 15:07:47 GMT 2023 , Edited by admin on Sat Dec 16 15:07:47 GMT 2023

PRIMARY

CAS

2643349-04-4

Created by admin on Sat Dec 16 15:07:47 GMT 2023 , Edited by admin on Sat Dec 16 15:07:47 GMT 2023

PRIMARY

FDA UNII

HO08KW5LSB

Created by admin on Sat Dec 16 15:07:47 GMT 2023 , Edited by admin on Sat Dec 16 15:07:47 GMT 2023

PRIMARY

From	To
1_22	1_97
2_22	2_97
2_131	4_213
2_144	2_200
2_258	2_318
1_131	3_213
2_364	2_422
3_22	3_87
3_136	3_195
4_22	4_87
4_136	4_195
1_144	1_200
1_223	2_223
1_226	2_226
1_258	1_318
1_364	1_422

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_294
N	2_294

Related Record Type Details


					HO08KW5LSB

Varokibart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL