DIETHYLAMMONIUM P-AMINOBENZOATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H7NO2.C4H11N
Molecular Weight	210.2728
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIETHYLAMMONIUM P-AMINOBENZOATE

Structure Search

SMILES

CCNCC.NC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=XMYMCNNZVQZVJW-UHFFFAOYSA-N

InChI=1S/C7H7NO2.C4H11N/c8-6-3-1-5(2-4-6)7(9)10;1-3-5-4-2/h1-4H,8H2,(H,9,10);5H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C7H7NO2
Molecular Weight	137.136
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H11N
Molecular Weight	73.1368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Bollettino - Societa Italiana di Biologia Sperimentale, Volume 27, Pages275-6, Journal, 1951
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14883411 | https://www.ncbi.nlm.nih.gov/pubmed/14391554 | https://www.ncbi.nlm.nih.gov/pubmed/14858664

Diethylammonium p-aminobenzoate is a powerful heart stimulant, with considerable effect on the uterus. Diethylammonium p-aminobenzoate protected the heart from the poisoning caused by procaine, maxicaine or xylocaine, and also against high doses of procaine amide. The substance passes the blood-spinal fluid barrier but high doses are necessary to find it in the spinal fluid, where it appears later than in the other body fluids. Diethylammonium p-aminobenzoate reduces the spontaneous activity of mice.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Climacteric 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13043489	Primary		Not Provided 511	Unknown Approved Use Glimepiride tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see Clinical Studies ( 14.1)

PubMed

Title	Date	PubMed
[Effects of N-diethylammonium-p-aminobenzoate in various medical syndromes].	1955-09-01	13274100

Patents

Sample Use Guides

In Vivo Use Guide

Chronic toxicity tests showed no mortality in rats by oral administration of 0.250 g/kg. per day for 60 days, but a slight loss in wt. was noted

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:33:18 GMT 2025` Edited by `admin` on `Mon Mar 31 23:33:18 GMT 2025`
Record UNII	HM0PW39IN5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIETHYLAMMONIUM P-AMINOBENZOATE

Common Name

English

P-AMINOBENZOIC ACID DIETHYLAMINE SALT

Preferred Name

English

AMINOBENZOIC ACID DIETHYLAMINE SALT

Common Name

English

BENZOIC ACID, 4-AMINO-, COMPD. WITH N-ETHYLETHANAMINE (1:1)

Common Name

English

P-AMINOBENZOIC ACID DIETHYLAMINE SALT [MI]

Common Name

English

NEVANIDE

Brand Name

English

Code System Code Type Description

MERCK INDEX

m1688

Created by admin on Mon Mar 31 23:33:18 GMT 2025 , Edited by admin on Mon Mar 31 23:33:18 GMT 2025

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Merck Index

CAS

6018-84-4

Created by admin on Mon Mar 31 23:33:18 GMT 2025 , Edited by admin on Mon Mar 31 23:33:18 GMT 2025

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FDA UNII

HM0PW39IN5

Created by admin on Mon Mar 31 23:33:18 GMT 2025 , Edited by admin on Mon Mar 31 23:33:18 GMT 2025

PRIMARY

PUBCHEM

22369

Created by admin on Mon Mar 31 23:33:18 GMT 2025 , Edited by admin on Mon Mar 31 23:33:18 GMT 2025

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Details

SMILES

InChI

CNS Activity

Originator

Approval Year

Conditions

Approved Use

PubMed

Patents

Sample Use Guides