Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H12N.Cl |
| Molecular Weight | 205.683 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Cl-].[NH3+]C1=CC=CC=C1C2=CC=CC=C2
InChI
InChIKey=QHYYXPLERUSFAV-UHFFFAOYSA-N
InChI=1S/C12H11N.ClH/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9H,13H2;1H
| Molecular Formula | C12H11N |
| Molecular Weight | 169.2224 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Detection and quantification of 4-ABP adducts in DNA from bladder cancer patients. | 2007-02 |
|
| Hydroxyl-specific fluorescence labeling of ABP-deoxyguanosine, PhIP-deoxyguanosine, and AFB1-formamidopyrimidine with BODIPY-FL. | 2006-12-15 |
|
| Redox-active silica nanoparticles. Part 1. Electrochemistry and catalytic activity of spherical, nonporous silica particles with nanometric diameters and covalently bound redox-active modifications. | 2006-12-05 |
|
| CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl. | 2006-12-01 |
|
| 4-Aminobiphenyl and DNA reactivity: case study within the context of the 2006 IPCS Human Relevance Framework for Analysis of a cancer mode of action for humans. | 2006-11-23 |
|
| N-acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice. | 2006-11 |
|
| Early events in the photochemistry of aryl azides from femtosecond UV/Vis spectroscopy and quantum chemical calculations. | 2006-10-18 |
|
| In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice. | 2006-10 |
|
| Quantification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human lymphoblastoid TK6 cells dosed with N-hydroxy-4-acetylaminobiphenyl and their relationship to mutation, toxicity, and gene expression profiling. | 2006-09-15 |
|
| Mutagenicity and antimutagenic effect of soymilk fermented with lactic acid bacteria and bifidobacteria. | 2006-08-15 |
|
| Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans. | 2006-07 |
|
| CYP1A2 and NAT2 phenotyping and 3-aminobiphenyl and 4-aminobiphenyl hemoglobin adduct levels in smokers and non-smokers. | 2006-06-15 |
|
| Bicyclic[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists. | 2006-05-15 |
|
| 4'-substituted-4-biphenylyloxenium ions: reactivity and selectivity in aqueous solution. | 2006-05-12 |
|
| Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies. | 2006-04-10 |
|
| Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers. | 2006-04 |
|
| Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster. | 2006-04 |
|
| Metabolic activation of bladder procarcinogens, 2-aminofluorene, 4-aminobiphenyl, and benzidine by Pseudomonas aeruginosa and other human endogenous bacteria. | 2006-04 |
|
| 2- and 4-Aminobiphenyls induce oxidative DNA damage in human hepatoma (Hep G2) cells via different mechanisms. | 2006-01-29 |
|
| Persistence of prostatic intraepithelial neoplasia after effective chemoprevention of microscopic prostate cancer with antiandrogen in a rat model. | 2006-01 |
|
| Levels of H-ras codon 61 CAA to AAA mutation: response to 4-ABP-treatment and Pms2-deficiency. | 2006-01 |
|
| 4-Aminobiphenyl induces liver DNA adducts in both neonatal and adult mice but induces liver mutations only in neonatal mice. | 2005-11-01 |
|
| The direct detection of an aryl azide excited state: an ultrafast study of the photochemistry of para- and ortho-biphenyl azide. | 2005-10-12 |
|
| Dietary supplementation with silymarin inhibits 3,2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in male F344 rats. | 2005-07-01 |
|
| A modified host cell reactivation assay to measure DNA repair capacity for removing 4-aminobiphenyl adducts: a pilot study of bladder cancer. | 2005-07 |
|
| Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines. | 2005-07 |
|
| High-performance liquid chromatography method for determination of N-glucuronidation of 4-aminobiphenyl by mouse, rat, and human liver microsomes. | 2005-05-15 |
|
| Substituent effects on the oxidation of substituted biphenyl congeners by type II methanotroph strain CSC1. | 2005-05 |
|
| Detection and quantification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human pancreas tissue using capillary liquid chromatography-microelectrospray mass spectrometry. | 2005-04 |
|
| Phenotypic anchoring of global gene expression profiles induced by N-hydroxy-4-acetylaminobiphenyl and benzo[a]pyrene diol epoxide reveals correlations between expression profiles and mechanism of toxicity. | 2005-04 |
|
| Levels of 4-aminobiphenyl-induced somatic H-ras mutation in mouse liver DNA correlate with potential for liver tumor development. | 2005-04 |
|
| Green tea extract modulates actin remodeling via Rho activity in an in vitro multistep carcinogenic model. | 2005-02-15 |
|
| Irreversible inactivation of arylamine N-acetyltransferases in the presence of N-hydroxy-4-acetylaminobiphenyl: a comparison of human and hamster enzymes. | 2005-02 |
|
| Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways. | 2005-01-14 |
|
| Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer. | 2004-10-06 |
|
| Chemical and enzymatic interactions of Direct Black 38 and Direct Brown 1 on release of carcinogenic amines. | 2004-09 |
|
| p-Nonylphenol pretreatment during the late neonatal period has no effect on 3,2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in male F344 rats. | 2004-08-30 |
|
| Discovery of small molecule antagonists of TRPV1. | 2004-07-16 |
|
| Static and dynamic model for 4-aminodiphenyl fluorescence quenching by carbontetrachloride in hexane. | 2004-07 |
|
| Carotenoids/vitamin C and smoking-related bladder cancer. | 2004-06-20 |
|
| Synthesis, characterization, and 32P-postlabeling of N-(deoxyguanosin)-4-aminobiphenyl 3'-phosphate adducts. | 2004-06 |
|
| Ecotoxicological evaluation of 4-aminobiphenyl using a test battery. | 2004-05 |
|
| Lack of modifying effects of 4-ter t-octylphenol and benzyl butyl phthalate on 3,2-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in rats. | 2004-04 |
|
| Modulation of rat and human cytochromes P450 involved in PhIP and 4-ABP activation by an aqueous extract of Phyllanthus orbicularis. | 2004-02 |
|
| Oxidation of benzidine and its derivatives by thyroid peroxidase. | 2004-02 |
|
| Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states. | 2003-12-17 |
|
| Identification of DNA adducts using HPLC/MS/MS following in vitro and in vivo experiments with arylamines and nitroarenes. | 2003-10 |
|
| Identification of aminobiphenyl derivatives in commercial hair dyes. | 2003-09 |
|
| Lack of carcinogenic risk in the prostate with transplacental and lactational exposure to bisphenol A in rats. | 2003-08 |
|
| 4-Aminobiphenyl. | 2002 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:36:09 GMT 2025
by
admin
on
Mon Mar 31 19:36:09 GMT 2025
|
| Record UNII |
HJN76WY88A
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| Record Status |
Validated (UNII)
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| Record Version |
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HJN76WY88A
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16601
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2185-92-4
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DTXSID4020163
Created by
admin on Mon Mar 31 19:36:09 GMT 2025 , Edited by admin on Mon Mar 31 19:36:09 GMT 2025
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