U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 19:21:28 GMT 2023
Edited
by admin
on Sat Dec 16 19:21:28 GMT 2023
Protein Type RECEPTOR
Protein Sub Type ACETYLCHOLINE RECEPTOR
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
HG7V4AMY2Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
α4β2 Nicotinic acetylcholine receptor
Common Name English
Neuronal acetylcholine receptor subunit alpha-4/Neuronal acetylcholine receptor subunit beta-2
Common Name English
α4β2 nAChR
Common Name English
Code System Code Type Description
FDA UNII
HG7V4AMY2Z
Created by admin on Sat Dec 16 19:21:29 GMT 2023 , Edited by admin on Sat Dec 16 19:21:29 GMT 2023
PRIMARY
UNIPROT
P43681
Created by admin on Sat Dec 16 19:21:29 GMT 2023 , Edited by admin on Sat Dec 16 19:21:29 GMT 2023
PRIMARY
UNIPROT
P17787
Created by admin on Sat Dec 16 19:21:29 GMT 2023 , Edited by admin on Sat Dec 16 19:21:29 GMT 2023
PRIMARY
From To
5_130 5_144
4_130 4_144
1_133 1_147
3_133 3_147
2_133 2_147
1_197 1_198
3_197 3_198
2_197 2_198
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_29
N 1_79
N 1_146
N 2_29
N 2_79
N 2_146
N 3_29
N 3_79
N 3_146
N 4_26
N 4_143
N 4_460
N 5_26
N 5_143
N 5_460
Related Record Type Details
RADIOLIGAND->TARGET
AGONIST -> TARGET
RADIOLIGAND->TARGET
Ki Values for Inhibiting ()-3H-Cytisine Binding to Rat Brain Synaptosomal Membranes
Ki
PARTIAL AGONIST->TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
PARTIAL AGONIST->TARGET
PARTIAL AGONIST->TARGET
PARTIAL AGONIST->TARGET
AGONIST -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL