TYROSINE-PROTEIN KINASE BTK C481F MUTANT

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:04:50 GMT 2025` Edited by `admin` on `Wed Apr 02 10:04:50 GMT 2025`
Protein Type	REGULATOR PROTEIN
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	HG6WHF74KQ
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

B-CELL PROGENITOR KINASE C481F MUTANT

Preferred Name

English

BRUTON TYROSINE KINASE C481F MUTANT

Common Name

English

BPK C481F MUTANT

Common Name

English

Code System Code Type Description

FDA UNII

HG6WHF74KQ

Created by admin on Wed Apr 02 10:04:50 GMT 2025 , Edited by admin on Wed Apr 02 10:04:50 GMT 2025

PRIMARY

Linkage Type	Residue Index
COORDINATION COMPOUND	1_142	1_153	1_154	1_164

Related Record Type Details


					KD68L3GRW2

INHIBITOR -> TARGET

Interaction Type:

IN-VITRO

Amount:


					PF6GPZ4DYT

DEGRADER->TARGET

Amount:

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_20] [1_54] [1_114] [1_622] [1_658]		DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[1_142] [1_153] [1_154] [1_164]	SITE_SPECIFIC	C3H1-TYPE ZINC FINGER	JKX41V9FYM
AMINO_ACID_SUBSTITUTION	[1_1]	SITE_SPECIFIC	N-ACETYLALANINE	26C4VY6Z0M
AMINO_ACID_SUBSTITUTION	[1_39] [1_222] [1_344] [1_360] [1_550] [1_616]	SITE_SPECIFIC	TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL