Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H24N2O4 |
| Molecular Weight | 380.437 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 2 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C(C=C1)\C=C\C(=O)NCCCCNC(=O)\C=C\C2=CC=C(O)C=C2
InChI
InChIKey=PYVBFDCHJDMSMM-FNCQTZNRSA-N
InChI=1S/C22H24N2O4/c25-19-9-3-17(4-10-19)7-13-21(27)23-15-1-2-16-24-22(28)14-8-18-5-11-20(26)12-6-18/h3-14,25-26H,1-2,15-16H2,(H,23,27)(H,24,28)/b13-7+,14-8+
| Molecular Formula | C22H24N2O4 |
| Molecular Weight | 380.437 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 2 |
| Optical Activity | NONE |
BIS-COUMARAMIDOBUTANE was isolated and purified from corn bran. It exhibited the strongest hydroxyl radical scavenging activity. The inhibitory effects of BIS-COUMARAMIDOBUTANE on melanogenesis is due to the inhibition of the intracellular tyrosinase activity. This indicate that BIS-COUMARAMIDOBUTANE from corn bran may be potential natural skin whitening agents. BIS-COUMARAMIDOBUTANE is registrated in International Cosmetic Ingredient Dictionary in Korea.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| New maltol glycosides from Flos Sophorae. | 2015-04 |
|
| The hunt for natural skin whitening agents. | 2009-12-10 |
|
| Antioxidant and antimelanogenic activities of polyamine conjugates from corn bran and related hydroxycinnamic acids. | 2007-05-16 |
|
| Inhibitory activity of corn-derived bisamide compounds against alpha-glucosidase. | 2003-01-01 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:40:09 GMT 2025
by
admin
on
Mon Mar 31 20:40:09 GMT 2025
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| Record UNII |
HFN1DLN96K
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| Record Status |
Validated (UNII)
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| Record Version |
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364048-94-2
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HFN1DLN96K
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admin on Mon Mar 31 20:40:09 GMT 2025 , Edited by admin on Mon Mar 31 20:40:09 GMT 2025
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