Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.971 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=C(Cl)C(Cl)=C2OC3=C(OC2=C1Cl)C=CC=C3
InChI
InChIKey=DJHHDLMTUOLVHY-UHFFFAOYSA-N
InChI=1S/C12H4Cl4O2/c13-7-8(14)10(16)12-11(9(7)15)17-5-3-1-2-4-6(5)18-12/h1-4H
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.971 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Dioxin-inducible transactivation in a chromosomal setting. Analysis of the acidic domain of the Ah receptor. | 2001-07-06 |
|
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptotic cell death and cytochrome P4501A expression in developing Fundulus heteroclitus embryos. | 2001-07 |
|
| Short heterodimer partner (SHP) orphan nuclear receptor inhibits the transcriptional activity of aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT). | 2001-06-01 |
|
| Alterations in follicle development, steroidogenesis, and gonadotropin receptor binding in a model of ovulatory blockade. | 2001-06 |
|
| Quantitative structure-property relationships for octanol-air partition coefficients of PCDD/Fs. | 2001-06 |
|
| In vivo antagonism of AhR-mediated gene induction by 3'-methoxy-4'-nitroflavone in TCDD-responsive lacZ mice. | 2001-06 |
|
| Subchronic Exposure of [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism. | 2001-06 |
|
| Congener profiles of PCDD/Fs in soil and vegetation samples collected near to a municipal waste incinerator. | 2001-05-25 |
|
| PAHs, PCDD/Fs, PCBs and HCB in leaves from Brisbane, Australia. | 2001-05-25 |
|
| The survey of PCDDs and PCDFs in the ambient air of the urban and industrial sites in Korea, 1998-99. | 2001-05-25 |
|
| Atmospheric baseline levels of PCDD and PCDF in the region of Oporto. | 2001-05-25 |
|
| Solvent extraction and tandem dechlorination for decontamination of soil. | 2001-05-25 |
|
| A high efficiency all glass sampling and concentration device for adsorptive semivolatile organics. | 2001-05-25 |
|
| Application of the new C18 speedisks to the analysis of polychlorinated dibenzo-p-dioxins and dibenzofurans in water and effluent samples. | 2001-05-25 |
|
| Rapid PCDD/PCDF screening method for fly ash with ion trap MS/MS. | 2001-05-25 |
|
| Convenient dioxin measuring method using an efficient sampling train, an efficient HPLC system and a highly sensitive HRGC/LRMS with a PTV injector. | 2001-05-25 |
|
| Optimisation and use of tandem-in-time mass spectrometry in comparison with immunoassay and HRGC/HRMS for PCDD/F screening. | 2001-05-25 |
|
| Quadrupole ion storage tandem mass spectrometry and high-resolution mass spectrometry: complementary application in the measurement of 2,3,7,8-chlorine substituted dibenzo-p-dioxins and dibenzofurans in US foods. | 2001-05-25 |
|
| Seveso: a teaching story. | 2001-05-25 |
|
| Effects of contamination level of dioxins and related chemicals on thyroid hormone and immune response systems in patients with "Yusho". | 2001-05-25 |
|
| Physiological modeling of a proposed mechanism of enzyme induction by TCDD. | 2001-05-21 |
|
| Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7. | 2001-05-15 |
|
| Arrest of rat molar tooth development by lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. | 2001-05-15 |
|
| Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced tumor promotion by 17 beta-estradiol in female Sprague--Dawley rats. | 2001-05-15 |
|
| Inhibitory effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cAMP-induced differentiation of rat C6 glial cell line. | 2001-05-15 |
|
| Regulation of subcellular localization of the aryl hydrocarbon receptor (AhR). | 2001-05-15 |
|
| 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin induces apoptosis in the dorsal midbrain of zebrafish embryos by activation of arylhydrocarbon receptor. | 2001-05-11 |
|
| Linking toxicology and epidemiology: the role of mechanistic modelling. | 2001-05-09 |
|
| Continuing research into Gulf War illness. | 2001-05-04 |
|
| Induction of CYP1A by benzo[k]fluoranthene in human hepatocytes: CYP1A1 or CYP1A2? | 2001-05-01 |
|
| Thermodynamic modeling of PCDD/Fs formation in thermal processes. | 2001-05-01 |
|
| How serious is dioxin's cancer risk? | 2001-05-01 |
|
| Degradation pathways of pentachlorophenol by photo-Fenton systems in the presence of iron(III), humic acid, and hydrogen peroxide. | 2001-05-01 |
|
| Interaction of estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in immature male chickens (Gallus domesticus). | 2001-05 |
|
| Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells. | 2001-05 |
|
| Correlation of PCDD/F emissions with operating parameters of municipal solid waste incinerators. | 2001-05 |
|
| An evaluation of the etiology of reduced CYP1A1 messenger RNA expression in the Atlantic tomcod from the Hudson River, New York, USA, using reverse transcriptase polymerase chain reaction analysis. | 2001-05 |
|
| De novo synthesis of polychlorinated dibenzo-p-dioxins and dibenzofurans on fly ash from a sintering process. | 2001-04-15 |
|
| Prevention of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the MCF-10A cell line: correlation with increased transforming growth factor alpha production. | 2001-04-15 |
|
| Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on fetal mouse urinary tract epithelium in vitro. | 2001-04-12 |
|
| Molecular biology of the Ah receptor and its role in carcinogenesis. | 2001-03-31 |
|
| Quantitative structure-property relationships on photodegradation of PCDD/Fs in cuticular waxes of laurel cherry (Prunus laurocerasus). | 2001-03-26 |
|
| Use of olive oil for soil extraction and ultraviolet degradation of polychlorinated dibenzo-p-dioxins and dibenzofurans. | 2001-03-15 |
|
| Regulation of cytochrome P450 in a primary culture of rainbow trout hepatocytes. | 2001-03 |
|
| Persistent organochlorine pollutants in eggs of colonial waterbirds from Galveston Bay and East Texas, USA. | 2001-03 |
|
| Dioxin in Vietnam: fighting a legacy of war. | 2001-03 |
|
| Chlorophyll derived from Chlorella inhibits dioxin absorption from the gastrointestinal tract and accelerates dioxin excretion in rats. | 2001-03 |
|
| Polychlorinated naphthalenes, -biphenyls, -dibenzo-p-dioxins, and -dibenzofurans in double-crested cormorants and herring gulls from Michigan waters of the Great Lakes. | 2001-02-01 |
|
| Accumulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin by rainbow trout (Onchorhynchus mykiss) at environmentally relevant dietary concentrations. | 2001-02 |
|
| Polychlorinated dibenzodioxins and dibenzofurans in butter from different states in Australia. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:55:17 GMT 2025
by
admin
on
Mon Mar 31 18:55:17 GMT 2025
|
| Record UNII |
HF5S8P28CC
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
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DTXSID7074030
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27785
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C092155
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35454
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30746-58-8
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HF5S8P28CC
Created by
admin on Mon Mar 31 18:55:17 GMT 2025 , Edited by admin on Mon Mar 31 18:55:17 GMT 2025
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PRIMARY |