U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry RACEMIC
Molecular Formula C25H27ClN2.2ClH.H2O
Molecular Weight 481.885
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MECLIZINE HYDROCHLORIDE

SMILES

O.Cl.Cl.CC1=CC(CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4)=CC=C1

InChI

InChIKey=KDLHYOMCWBWLMM-UHFFFAOYSA-N
InChI=1S/C25H27ClN2.2ClH.H2O/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23;;;/h2-13,18,25H,14-17,19H2,1H3;2*1H;1H2

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C25H27ClN2
Molecular Weight 390.948
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: Description was created based on several sources, including https://www.drugs.com/meclizine.html

Meclizine, a piperazine-derivative H1-receptor antagonist similar to buclizine, cyclizine, and hydroxyzine, is used as an antivertigo/antiemetic agent. Meclizine is used in the management of nausea, vomiting, and dizziness associated with motion sickness and vertigo in diseases affecting the vestibular apparatus. Along with its actions as an antagonist at H1-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Meclizine depresses labyrinth excitability and vestibular stimulation and may affect the medullary chemoreceptor trigger zone. It is sold under the brand names Bonine, Bonamine, Antivert, Postafen, Sea Legs, and Dramamine II.

CNS Activity

CNS Active
4002
Curator's Comment: central nervous system depressant

Approval Year

1954
119
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8504
Agonist
2752
Ethanolamine-phosphate cytidylyltransferase
8
Target ID: Q922E4
Gene ID: 68671.0
Gene Symbol: Pcyt2
Target Organism: Mus musculus (Mouse)
Inhibitor
8504
 31.0 µM [Ki]
Antagonist
2849
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8583
ANTIVERT

Approved Use

Effective: Management of nausea and vomiting, and dizziness associated with motion sickness. Possibly Effective: Management of vertigo associated with diseases affecting the vestibular system.

Launch Date

2012
Primary
Approved
8583
ANTIVERT

Approved Use

Effective: Management of nausea and vomiting, and dizziness associated with motion sickness. Possibly Effective: Management of vertigo associated with diseases affecting the vestibular system.

Launch Date

2012
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
99.43 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/21903894/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
99.43 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/21903894/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
130 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FASTED
223 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg 2 times / day multiple, oral
dose: 25 mg
route of administration: Oral
experiment type: MULTIPLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FED
149 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FED
131.3 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg 1 times / day steady-state, oral
dose: 25 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FASTED
210.8 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg 2 times / day steady-state, oral
dose: 25 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FED
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
564.03 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/21903894/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
564.03 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/21903894/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
671 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FASTED
2030 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FED
656 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg 1 times / day steady-state, oral
dose: 25 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FASTED
1891 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg 2 times / day steady-state, oral
dose: 25 mg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FED
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
5.24 h
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/21903894/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
5.24 h
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/21903894/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
8.5 h
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FASTED
3.6 h
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/32282831/
25 mg single, oral
dose: 25 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
MECLIZINE plasma
Homo sapiens
population: UNHEALTHY
age: CHILD
sex: FEMALE / MALE
food status: FED
Doses

Doses

DosePopulationAdverse events​
100 mg 1 times / day multiple, oral
Recommended
Dose: 100 mg, 1 times / day
Route: oral
Route: multiple
Dose: 100 mg, 1 times / day
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/010721s058lbl.pdf
unhealthy, ADULT
Health Status: unhealthy
Age Group: ADULT
Sex: M+F
Food Status: UNKNOWN
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/010721s058lbl.pdf
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/010721s058lbl.pdf
50 mg single, oral
Recommended
Dose: 50 mg
Route: oral
Route: single
Dose: 50 mg
Sources:
https://pubmed.ncbi.nlm.nih.gov/10674593/
healthy, ADULT
Health Status: healthy
Age Group: ADULT
Sex: F
Food Status: UNKNOWN
Sources:
https://pubmed.ncbi.nlm.nih.gov/10674593/
Other AEs: Drowsiness...
Other AEs:
Drowsiness (30%)
Sources:
https://pubmed.ncbi.nlm.nih.gov/10674593/
25 mg 2 times / day multiple, oral
Recommended
Dose: 25 mg, 2 times / day
Route: oral
Route: multiple
Dose: 25 mg, 2 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/32282831
unhealthy, 5-10
Health Status: unhealthy
Age Group: 5-10
Sex: M+F
Sources:
https://pubmed.ncbi.nlm.nih.gov/32282831
Sources:
https://pubmed.ncbi.nlm.nih.gov/32282831
25 mg single, oral
Recommended
Dose: 25 mg
Route: oral
Route: single
Dose: 25 mg
Sources:
https://pubmed.ncbi.nlm.nih.gov/32282831
unhealthy, 6-10
Health Status: unhealthy
Age Group: 6-10
Sex: M+F
Sources:
https://pubmed.ncbi.nlm.nih.gov/32282831
Sources:
https://pubmed.ncbi.nlm.nih.gov/32282831
100 mg multiple, oral
Recommended
Dose: 100 mg
Route: oral
Route: multiple
Dose: 100 mg
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/010721s063lbl.pdf
unhealthy
Health Status: unhealthy
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/010721s063lbl.pdf
Other AEs: Drowsiness...
Other AEs:
Drowsiness
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/010721s063lbl.pdf
AEs

AEs

AESignificanceDosePopulation
Drowsiness 30%
50 mg single, oral
Recommended
Dose: 50 mg
Route: oral
Route: single
Dose: 50 mg
Sources:
https://pubmed.ncbi.nlm.nih.gov/10674593/
healthy, ADULT
Health Status: healthy
Age Group: ADULT
Sex: F
Food Status: UNKNOWN
Sources:
https://pubmed.ncbi.nlm.nih.gov/10674593/
Drowsiness
100 mg multiple, oral
Recommended
Dose: 100 mg
Route: oral
Route: multiple
Dose: 100 mg
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/010721s063lbl.pdf
unhealthy
Health Status: unhealthy
Sources:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/010721s063lbl.pdf
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B2-0833
http://www.3bsc.com/index/pro_info.php?id=20189
AA Blocks
AA007D5D
http://www.aablocks.com/goods/Goods/detail?id=AA007D5D
Aaron Chemicals
AR007DX5
http://www.aaronchem.com/1104-22-9
Aaron Chemicals
AR00IAUE
http://www.aaronchem.com/569-65-3
abcr GmbH
AB349167
http://www.abcr.de/shop/en/AB349167
abcr GmbH
AB505723
http://www.abcr.de/shop/en/AB505723
AbMole Bioscience
M3213
http://www.abmole.com/products/meclizine-dihydrochloride.html
Achemo Scientific Limited
AC-65051
http://www.achemo.com/search/?Keyword=569-65-3
Achemtek
0104-027376
http://www.achemtek.com/1104-22-9
AHH Chemical co.,ltd
API-1805
http://www.ahhchemical.com/product/API-1805.html
AK Scientific, Inc. (AKSCI)
J10216
http://www.aksci.com/item_detail.php?cat=J10216
AK Scientific, Inc. (AKSCI)
R831
http://www.aksci.com/item_detail.php?cat=R831
AK Scientific, Inc. (AKSCI)
W0051
http://www.aksci.com/item_detail.php?cat=W0051
Alfa Chemistry
AP1104229
https://reagents.alfa-chemistry.com/product/meclizine-dihydrochloride-cas-1104-22-9-1600.html
Alfa Chemistry
AP31884772
https://reagents.alfa-chemistry.com/product/meclizine-hydrochloride-cas-31884-77-2-9895.html
Alichem
139001864
http://www.alichem.com/en/products/569-65-3.html
Ambinter
Amb10843602
http://www.ambinter.com/reference/10843602
Ark Pharm
AK-54924
http://www.arkpharminc.com/products/1104-22-9.html
Aurora Fine Chemicals LLC
A24.088.326
http://online.aurorafinechemicals.com/info?ID=A24.088.326
Aurora Fine Chemicals LLC
K06.253.021
http://online.aurorafinechemicals.com/info?ID=K06.253.021
Aurora Fine Chemicals LLC
K06.994.411
http://online.aurorafinechemicals.com/info?ID=K06.994.411
Aurum Pharmatech LLC
NE58451
http://www.Aurumpharmatech.com/Product/ProductDetails/NE58451
BioChemPartner
BCP02929
http://www.biochempartner.com/1104-22-9-BCP02929
BioChemPartner
BCP13363
http://www.biochempartner.com/31884-77-2-BCP13363
BioChemPartner
BCP28339
http://www.biochempartner.com/189298-48-4-BCP28339
BioCrick
BCC9017
http://www.biocrick.com/Meclizine-hydrochloride-BCC9017.html
BioSynth
J-002420
https://www.biosynth.com/en/products/all-products/products/J-002420.html
BioSynth
Q-201344
https://www.biosynth.com/en/products/life-science/other-biochemicals/products/Q-201344.html
BLD Pharm
BD137308
http://www.bldpharm.com/products/569-65-3.html
BLD Pharm
BD137309
http://www.bldpharm.com/products/1104-22-9.html
BLD Pharm
BD137310
http://www.bldpharm.com/products/31884-77-2.html
BOC Sciences
1104-22-9
https://www.bocsci.com/meclizine-2hcl-cas-1104-22-9-item-84-81622.html
BOC Sciences
31884-77-2
https://www.bocsci.com/meclizine-hydrochloride-cas-31884-77-2-item-65938.html
BOC Sciences
569-65-3
https://www.bocsci.com/meclozine-cas-569-65-3-item-345566.html
Chem Scene
CS-2388
http://www.chemscene.com/1104-22-9.html
Chemenu
CM110387
http://www.chemenu.com/products/CM110387
ChemMol
44008702
http://www.chemmol.com/chemmol/44008702.html
ChemMol
49412604
http://www.chemmol.com/chemmol/49412604.html
ChemMol
49427857
http://www.chemmol.com/chemmol/49427857.html
ChemMol
99106552
http://www.chemmol.com/chemmol/99106552.html
ChemShuttle
151551
http://www.chemshuttle.com/catalogsearch/result/?q=1104-22-9&cat=
Chemspace
CSSB00000746775
https://chem-space.com/CSSB00000746775
Chemspace
CSSB00000753008
https://chem-space.com/CSSB00000753008
Chemspace
CSSB00015288267
https://chem-space.com/CSSB00015288267
Clearsynth
CS-EB-01272
https://www.clearsynth.com/en/CSEB01272.html
Clearsynth
CS-ER-01264
https://www.clearsynth.com/en/CSER01264.html
Clearsynth
CS-O-01897
http://www.clearsynth.com/en/CS-O-01897.html
Clearsynth
CS-P-01653
https://www.clearsynth.com/en/CSP01653.html
Combi-Blocks
QA-2598
http://www.combi-blocks.com/cgi-bin/find.cgi?QA-2598
CSNpharm
CSN11366
https://www.csnpharm.com/products/meclizine-dihydrochloride.html
DC Chemicals
DC7757
http://www.dcchemicals.com/product_show-_R_Meclizine.html
Debye Scientific
DB-040919
http://www.debyesci.com/cas_1104-22-9.html
Enamine
EN300-58334
https://www.enaminestore.com/catalog/EN300-58334
Enamine
EN300-71543
https://www.enaminestore.com/catalog/EN300-71543
Enamine
Z53003552
https://www.enaminestore.com/catalog/Z53003552
eNovation Chemicals
D523825
https://www.enovationchem.com/ProductDetails.asp?ProductID=D523825
eNovation Chemicals
D618485
https://www.enovationchem.com/ProductDetails.asp?ProductID=D618485
Finetech
FT-0603544
http://www.finetechnology-ind.com/prod/detail/pub/1104-22-9.html
Finetech
FT-0659103
http://www.finetechnology-ind.com/prod/detail/pub/31884-77-2.html
Glentham Life Sciences
GP7447
http://www.glentham.com/products/product/GP7447/
Hairui
HR101508
http://www.hairuichem.com/en/product/31884-77-2.html
Hairui
HR131737
http://www.hairuichem.com/en/product/1104-22-9.html
Hairui
HR133843
http://www.hairuichem.com/en/product/569-65-3.html
iChemical
EBD32645
http://www.ichemical.com/chemicals/cas-1104-22-9
iChemical
EBD8359
http://www.ichemical.com/chemicals/cas-569-65-3
Lab Network
LN00174195
https://labnetwork.com/frontend-app/p/#!/moleculedetails/LN00174195
Lab Network
LN01796008
https://labnetwork.com/frontend-app/p/#!/moleculedetails/LN01796008
LGC Standards
LGCFOR0586.00
https://www.lgcstandards.com/US/en/p/LGCFOR0586.00
LGC Standards
MM0586.00-0250
https://www.lgcstandards.com/US/en/p/MM0586.00-0250
Matrix Scientific
75920
https://www.matrixscientific.com/075920.html
mcule
MCULE-4211025798
https://mcule.com/MCULE-4211025798/
mcule
MCULE-6706083805
https://mcule.com/MCULE-6706083805
mcule
MCULE-7463916552
https://mcule.com/MCULE-7463916552/
MedChem Express
HY-B0349
https://www.medchemexpress.com/Meclizine-dihydrochloride.html
MolPort
MolPort-002-069-043
https://www.molport.com/shop/molecule-link/MolPort-002-069-043
MolPort
MolPort-003-666-221
https://www.molport.com/shop/molecule-link/MolPort-003-666-221
MolPort
MolPort-019-995-743
https://www.molport.com/shop/molecule-link/MolPort-019-995-743
MuseChem
A000946
https://www.musechem.com/product/A000946.html
Oakwood
79238
http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=64412&ExtHyperLink=1
OChem
12500
http://www.ocheminc.com/index.php?act=psearch&pid=569M653
OChem
30709
http://www.ocheminc.com/index.php?act=psearch&pid=104M229
Parchem
29350
http://www.parchem.com/chemical-supplier-distributor/Meclizine-019350.aspx
Parchem
29352
http://www.parchem.com/chemical-supplier-distributor/Meclizine-Hydrochloride-019352.aspx
Parchem
29356
http://www.parchem.com/chemical-supplier-distributor/Meclozine-019356.aspx
Selleck Chemicals
S1986
http://www.selleckchem.com/products/meclizine-dihydrochloride.html
Sigma-Aldrich
M0220000_SIAL
https://www.sigmaaldrich.com/catalog/product/sial/m0220000?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich
PH009750_ALDRICH
https://www.sigmaaldrich.com/catalog/product/aldrich/ph009750
Smolecule
S534869
http://www.smolecule.com/products/s534869
Smolecule
S573626
https://www.smolecule.com/products/s573626
TCI (Tokyo Chemical Industry)
M2755
http://www.tcichemicals.com/eshop/en/us/commodity/M2755/index.html
THE BioTek
bt-274528
https://www.thebiotek.com/product/inhibitors/bt-274528
Tocris
4245
https://www.tocris.com/products/meclizine-dihydrochloride_4245
Vesino Industrial Co Ltd
VA11241
http://www.vsnchem.com/goto/product/22579/
VladaChem
VL274637-25G
https://www.vladachem.com/product.php?products=1104-22-9
Yuhao Chemical
JZ3796
http://www.chemyuhao.com/569-65-3.html
Yuhao Chemical
XJ1544
http://www.chemyuhao.com/1104-22-9.html
PubMed

PubMed

TitleDatePubMed
Memory loss, confusion, and disorientation in an elderly woman taking meclizine.
1987 May
Pentoxifylline-induced musical hallucinations.
1993 Aug
Discovery of molecular mechanisms of neuroprotection using cell-based bioassays and oligonucleotide arrays.
2002 Oct 29
Auditory hallucinations elicited by combined meclizine and metaxalone use at bedtime.
2004 Nov
Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR.
2004 Oct
FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.
2013 Sep 5
Patents

Patents

JPS60204712A
8

Sample Use Guides

In Vivo Use Guide
Usual Adult Dose for Vertigo -25 to 100 mg orally per day in divided doses Usual Adult Dose for Motion Sickness -Initial Dose: 25 to 50 mg orally 1 hour before travel -Maintenance Dose: Repeat dose every 24 hours if needed
Route of Administration: Oral
In Vitro Use Guide
50 uM meclizine inhibited respiratory growth of human skin fibroblasts
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:25:29 GMT 2025
Edited
by admin
on Mon Mar 31 18:25:29 GMT 2025
Record UNII
HDP7W44CIO
Record Status Validated (UNII)
Record Version
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Name Type Language
MECLIZINE HYDROCHLORIDE
JAN   ORANGE BOOK   USP   VANDF  
Common Name English
MECLIZINE DIHYDROCHLORIDE MONOHYDRATE
MI  
Preferred Name English
MECLIZINE DIHYDROCHLORIDE MONOHYDRATE, (±)-
Common Name English
UCB-5062
Code English
Meclozine hydrochloride monohydrate [WHO-DD]
Common Name English
MECLIZINE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
BONINE
Brand Name English
MECLIZINE HYDROCHLORIDE [USP-RS]
Common Name English
PIPERAZINE, 1-((4-CHLOROPHENYL)PHENYLMETHYL)-4-((3-METHYLPHENYL)METHYL)-, DIHYDROCHLORIDE, MONOHYDRATE
Common Name English
MECLIZINE HCL
Common Name English
MECLIZINE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
ANCOLAN
Brand Name English
AGYRAX
Brand Name English
BONAMINE
Common Name English
MECLIZINE DIHYDROCHLORIDE MONOHYDRATE [MI]
Common Name English
POSTAFEN
Brand Name English
MECLIZINE HYDROCHLORIDE [VANDF]
Common Name English
ANTIVERT
Brand Name English
NSC-757094
Code English
1-(P-CHLORO-.ALPHA.-PHENYLBENZYL)-4-(M-METHYLBENZYL)PIPERAZINE DIHYDROCHLORIDE MONOHYDRATE
Common Name English
MECLIZINE HYDROCHLORIDE [JAN]
Common Name English
(±)-MECLIZINE DIHYDROCHLORIDE MONOHYDRATE
Common Name English
MECLOZINE HYDROCHLORIDE MONOHYDRATE
WHO-DD  
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29578
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
NCI_THESAURUS C267
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
CFR 21 CFR 336.50
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
CFR 21 CFR 336.10
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
Code System Code Type Description
RXCUI
82041
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY RxNorm
SMS_ID
300000040285
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
EPA CompTox
DTXSID30953792
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
DAILYMED
HDP7W44CIO
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
PUBCHEM
173612
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
MERCK INDEX
m7118
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY Merck Index
RS_ITEM_NUM
1377009
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
FDA UNII
HDP7W44CIO
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
NCI_THESAURUS
C29245
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
CAS
31884-77-2
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
DRUG BANK
DBSALT000678
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
ChEMBL
CHEMBL1623
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
NSC
757094
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
EVMPD
SUB35563
Created by admin on Mon Mar 31 18:25:29 GMT 2025 , Edited by admin on Mon Mar 31 18:25:29 GMT 2025
PRIMARY
Related Record Type Details
Structure of MECLIZINE HYDROCHLORIDE ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of MECLIZINE HYDROCHLORIDE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of MECLIZINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of 3-METHYLBENZYL ALCOHOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 4-CHLOROBENZHYDROL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of MECLIZINE O-CHLORO ISOMER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 1,4-BIS(3-METHYLBENZYL) PIPERAZINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of MECLIZINE
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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