MITOMETH

Investigational

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H12Cl4
Molecular Weight	334.068
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(Cl)(Cl)C(C1=CC=C(Cl)C=C1)C2=CC=CC=C2Cl

InChI

InChIKey=MOTIYCLHZZLHHQ-UHFFFAOYSA-N

InChI=1S/C15H12Cl4/c1-15(18,19)14(10-6-8-11(16)9-7-10)12-4-2-3-5-13(12)17/h2-9,14H,1H3

HIDE SMILES / InChI

Molecular Formula	C15H12Cl4
Molecular Weight	334.068
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8453685

Mitometh, a methylated homolog of mitotane possesses an adrenalytic activity and has been studied for the treatment of adrenal cancer. Experiments on animals and on human cell lines have shown that mitometh was not effective in the therapy of adrenal cancer.

Approval Year

PubMed

Title	Date	PubMed
Comparison of the adrenalytic activity of mitotane and a methylated homolog on normal adrenal cortex and adrenal cortical carcinoma.	1993	8453685

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:46:28 GMT 2025` Edited by `admin` on `Mon Mar 31 21:46:28 GMT 2025`
Record UNII	H8MTN7XVC2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DDP

Preferred Name

English

MITOMETH

Common Name

English

BENZENE, 1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)PROPYL)-

Systematic Name

English

Code System Code Type Description

FDA UNII

H8MTN7XVC2