SUDEXANOX

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H23NO5S
Molecular Weight	401.476
Optical Activity	( + / - )
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCC1=CC(=CC2=C1OC3=CC=C(C=C3C2=O)C(O)=O)S(C)(=N)=O

InChI

InChIKey=DIGXMFZQXQUVMR-UHFFFAOYSA-N

InChI=1S/C21H23NO5S/c1-3-4-5-6-7-13-10-15(28(2,22)26)12-17-19(23)16-11-14(21(24)25)8-9-18(16)27-20(13)17/h8-12,22H,3-7H2,1-2H3,(H,24,25)

HIDE SMILES / InChI

Molecular Formula	C21H23NO5S
Molecular Weight	401.476
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2897466 | https://www.ncbi.nlm.nih.gov/pubmed/3760070 | https://www.ncbi.nlm.nih.gov/pubmed/430479

Sudexanox is a xanthone derivative patented by French pharmaceutical company Roussel-UCLAF for the treatment of allergy, allergic asthma, and asthmatic bronchitis. In preclinical studies, Sudexanox possesses potent activity in the IgE-induced rat passive cutaneous anaphylaxis model.

Originator

Approval Year

PubMed

Title	Date	PubMed
High-performance liquid chromatographic method for the determination of sudexanox as the free acid in plasma.	1986 Aug 2	3760070

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:22:27 GMT 2023` Edited by `admin` on `Fri Dec 15 16:22:27 GMT 2023`
Record UNII	H6C0F5AD7D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SUDEXANOX

Official Name

English

sudexanox [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29712