2,4-DIAMINOPHENOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H8N2O
Molecular Weight	124.1405
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=CC(N)=C(O)C=C1

InChI

InChIKey=XIWMTQIUUWJNRP-UHFFFAOYSA-N

InChI=1S/C6H8N2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,7-8H2

HIDE SMILES / InChI

Molecular Formula	C6H8N2O
Molecular Weight	124.1405
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12621517 | https://cosmeticsinfo.org/ingredient/24-diaminophenol | https://journals.sagepub.com/doi/abs/10.3109/10915819409140610?journalCode=ijta

2,4-Diaminophenol dihydrochloride is used in the manufacture of dyes and as a color accelerator in photographic developers. 2,4-Diaminophenol is an ingredient of hair dyes and colors. 2,4-Diaminophenol and 2,4-Diaminophenol Dihydrochloride are considered safe for use in hair dyes at concentrations up to 0.2% (as the free base). 2,4-Diaminophenol Dihydrochloride is approved for use in Japan in cosmetic.

Approval Year

PubMed

Title	Date	PubMed
Simple, rapid reagent-injection spectrophotometric determination of fluorides in pharmaceutical formulations.	2001 Jul	11377081
Surfactant-assisted UV-photolysis of nitroarenes.	2002 Jan	11838434
Patch testing with the irritant sodium lauryl sulfate (SLS) is useful in interpreting weak reactions to contact allergens as allergic or irritant.	2003 Feb	12694214
LC-MS-MS analysis of 2,4-dinitrophenol and its phase I and II metabolites in a case of fatal poisoning.	2007 Jan-Feb	17389084

Patents

Sample Use Guides

In Vivo Use Guide

Groups of five rats of each sex received doses of 0, 6, 13, 25, 50, or 100 mg/kg and groups of five mice of each sex received doses of 0, 13, 25, 50, 100, or 200 mg/kg of 2,4-diaminophenol dihydrochloride in corn oil by gavage.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 00:39:33 GMT 2023` Edited by `admin` on `Sat Dec 16 00:39:33 GMT 2023`
Record UNII	H691WBT7OS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,4-DIAMINOPHENOL

Official Name

English

NSC-5727

Code

English

PHENOL, 2,4-DIAMINO-

Systematic Name

English

2,4-DIAMINOPHENOL [MI]

Common Name

English

4-HYDROXY-1,3-BENZENEDIAMINE

Systematic Name

English

2,4-DIAMINOPHENOL [INCI]

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

202-459-4