Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H3IN2O2 |
| Molecular Weight | 237.9833 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
IC1=CNC(=O)NC1=O
InChI
InChIKey=KSNXJLQDQOIRIP-UHFFFAOYSA-N
InChI=1S/C4H3IN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
| Molecular Formula | C4H3IN2O2 |
| Molecular Weight | 237.9833 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Synthesis and properties of triplex-forming oligonucleotides containing 2'-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine. | 2010-09-01 |
|
| Herpes simplex virus-1 helicase-primase: roles of each subunit in DNA binding and phosphodiester bond formation. | 2009-11-03 |
|
| Structures of native human thymidine phosphorylase and in complex with 5-iodouracil. | 2009-09-04 |
|
| Synthesis of N-substituted 5-iodouracils as antimicrobial and anticancer agents. | 2009-07-27 |
|
| [Myocardial single photon emission tomography imaging of reporter gene expression in rabbits]. | 2009-06 |
|
| Aluminium(III), chromium(III) and iron(III) complexes with 5-iodouracil and 5-iodouracil-histidine and their antitumour activity. | 2009-02 |
|
| Redetermination of 5-iodo-uracil. | 2008-01-04 |
|
| A simple crosslinking method, CLAMP, to map the sites of RNA-contacting domains within a protein. | 2008 |
|
| N-1 regioselective Michael-type addition of 5-substituted uracils to (2-hydroxyethyl) acrylate. | 2007-11-08 |
|
| Functionalization of unprotected uracil derivatives using the halogen-magnesium exchange. | 2007-04-26 |
|
| Synthesis of novel 2'-methyl carbovir analogues as potent antiviral agents. | 2007-02 |
|
| Synthesis of new, base-modified PNA monomers. | 2007 |
|
| The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine. | 2006-08-01 |
|
| Evaluation of novel one-electron reduction with metal in DNA. | 2006 |
|
| Simple synthesis of novel acyclic (e)-bromovinyl nucleosides as potential antiviral agents. | 2006 |
|
| Identification of base-specific contacts in protein-DNA complexes by photocrosslinking and mass spectrometry: a case study using the restriction endonuclease SsoII. | 2005-07 |
|
| Influence of halogenation on the properties of uracil and its noncovalent interactions with alkali metal ions. Threshold collision-induced dissociation and theoretical studies. | 2004-12-15 |
|
| Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet. | 2004-05-26 |
|
| Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides. | 2004 |
|
| Nucleobase modified peptide nucleic acid. | 2003-10-21 |
|
| Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. | 2002-09-12 |
|
| Synthesis of 1-(2-hydroxy-3-methoxypropyl)uracils and their activity against L1210 and macrophage raw 264.7 cells. | 2002-08-17 |
|
| Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer. | 2002-04-12 |
|
| Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex in solution: the protein-induced DNA kink causes intrastrand hydrogen abstraction from the 5-methyl of thymine at the 5' side. | 2002-03-13 |
|
| Mass spectrometric analysis of a UV-cross-linked protein-DNA complex: tryptophans 54 and 88 of E. coli SSB cross-link to DNA. | 2001-10 |
|
| N(1)-C(5')-linked dimer hydrates of 5-substituted uracils produced by anodic oxidation in aqueous solution. | 2001-04-06 |
|
| Synthesis of pyrrolidine C-nucleosides via Heck reaction. | 2001-02-08 |
|
| Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | 1994-08-17 |
|
| Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA. | 1986-03-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:24:43 GMT 2025
by
admin
on
Mon Mar 31 22:24:43 GMT 2025
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| Record UNII |
H59BRK500M
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| Record Status |
Validated (UNII)
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| Record Version |
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Systematic Name | English | ||
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Preferred Name | English | ||
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C542
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696-07-1
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DTXSID3061009
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211-788-2
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DB03554
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69672
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57848
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H59BRK500M
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C122724
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