U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 19:33:47 GMT 2023
Edited
by admin
on Sat Dec 16 19:33:47 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
H533QU433M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Enlonstobart
INN  
Official Name English
SG-001
Code English
Immunoglobulin G4 [221-proline], anti-(human programmed cell death protein 1) (human monoclonal SG001 γ4-chain), disulfide with human monoclonal SG001 κ-chain, dimer
Common Name English
Immunoglobulin G4-kappa, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279)], Homo sapiens monoclonal antibody
Common Name English
enlonstobart [INN]
Common Name English
SG001
Code English
gamma4 heavy chain Homo sapiens (1-440) [VH(Homo sapiens IGHV3-33*01 (92.8%) -(IGHD)-IGHJ4*01 (100%), CDR-IMGT [8.8.6] (26-33.51-58.97-102)) (1-113) -Homo sapiens IGHG4*01, nG4m(a)CH2 L92, G4v5 h P10 (CH1 (114-211), hinge 1-12 S10>P (221) (212-223), CH2
Common Name English
Code System Code Type Description
INN
12413
Created by admin on Sat Dec 16 19:33:47 GMT 2023 , Edited by admin on Sat Dec 16 19:33:47 GMT 2023
PRIMARY
CAS
2651230-53-2
Created by admin on Sat Dec 16 19:33:47 GMT 2023 , Edited by admin on Sat Dec 16 19:33:47 GMT 2023
PRIMARY
NCI_THESAURUS
C182009
Created by admin on Sat Dec 16 19:33:47 GMT 2023 , Edited by admin on Sat Dec 16 19:33:47 GMT 2023
PRIMARY
FDA UNII
H533QU433M
Created by admin on Sat Dec 16 19:33:47 GMT 2023 , Edited by admin on Sat Dec 16 19:33:47 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_127 4_214
2_140 2_196
2_254 2_314
1_127 3_214
2_360 2_418
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_140 1_196
1_219 2_219
1_222 2_222
1_254 1_314
1_360 1_418
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_290
N 2_290
Related Record Type Details
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL