Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H17NO6 |
| Molecular Weight | 247.2451 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C#N
InChI
InChIKey=QLTCHMYAEJEXBT-ZEBDFXRSSA-N
InChI=1S/C10H17NO6/c1-10(2,4-11)17-9-8(15)7(14)6(13)5(3-12)16-9/h5-9,12-15H,3H2,1-2H3/t5-,6-,7+,8-,9+/m1/s1
| Molecular Formula | C10H17NO6 |
| Molecular Weight | 247.2451 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| High cassava production and low dietary cyanide exposure in mid-west Nigeria. | 2001 Feb |
|
| Identification of essential active-site residues in the cyanogenic beta-glucosidase (linamarase) from cassava (Manihot esculenta Crantz) by site-directed mutagenesis. | 2001 Jan 15 |
|
| Effect of yam (Dioscorea cayenensis) and dasheen (Colocassia esculenta) extracts on the kidney of streptozotocin-induced diabetic rats. | 2001 Sep |
|
| Linamarase expression in cassava cultivars with roots of low- and high-cyanide content. | 2002 Aug |
|
| Loss of residual cyanogens in a cassava food during short-term storage. | 2002 Jul |
|
| [The canine model in the gene therapy of glioblastoma]. | 2003 |
|
| New aspects in pathogenesis of konzo: neural cell damage directly caused by linamarin contained in cassava (Manihot esculenta Crantz). | 2003 Aug |
|
| Cyanogenic potential in cassava and its influence on a generalist insect herbivore Cyrtomenus bergi (Hemiptera: Cydnidae). | 2003 Dec |
|
| Generation of cyanogen-free transgenic cassava. | 2003 Jul |
|
| Fish are central in the diet of Amazonian riparians: should we worry about their mercury concentrations? | 2003 Jul |
|
| Raman spectroscopic analysis of cyanogenic glucosides in plants: development of a flow injection surface-enhanced Raman scatter (FI-SERS) method for determination of cyanide. | 2004 Feb |
|
| Over-expression of hydroxynitrile lyase in transgenic cassava roots accelerates cyanogenesis and food detoxification. | 2004 Jan |
|
| Cassava cyanogens and fish mercury are high but safely consumed in the diet of native Amazonians. | 2004 Mar |
|
| Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus. | 2004 May |
|
| Engineering cyanogen synthesis and turnover in cassava (Manihot esculenta). | 2004 Nov |
|
| A geminivirus-induced gene silencing system for gene function validation in cassava. | 2004 Nov |
|
| Purification and characterization of an intracellular beta-glucosidase from the methylotrophic yeast Pichia pastoris. | 2005 Dec |
|
| Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology. | 2005 Sep |
|
| The Unitarian Hypothesis for the aetiology of diabetes mellitus. | 2006 |
|
| Linamarase activities in Bacillus spp. responsible for thermophilic aerobic digestion of agricultural wastes for animal nutrition. | 2007 |
|
| Sequencing analysis of 20,000 full-length cDNA clones from cassava reveals lineage specific expansions in gene families related to stress response. | 2007 Dec 20 |
|
| The cyanogenic glucoside composition of Zygaena filipendulae (Lepidoptera: Zygaenidae) as effected by feeding on wild-type and transgenic lotus populations with variable cyanogenic glucoside profiles. | 2007 Jan |
|
| Cytotoxicity of purified cassava linamarin to a selected cancer cell lines. | 2007 Jul |
|
| Intimate roles for cyanogenic glucosides in the life cycle of Zygaena filipendulae (Lepidoptera, Zygaenidae). | 2007 Nov |
|
| Transgenic approaches for cyanogen reduction in cassava. | 2007 Sep-Oct |
|
| The beta-glucosidases responsible for bioactivation of hydroxynitrile glucosides in Lotus japonicus. | 2008 Jul |
|
| Leaching of cyanogenic glucosides and cyanide from white clover green manure. | 2008 Jun |
|
| Glioma regression in vitro and in vivo by a suicide combined treatment. | 2008 Mar |
|
| [The killing effect and bystander effect of linamarase/linamarin suicide gene system on human hepatocellular carcinoma cell line HepG2 in vitro]. | 2008 Mar |
|
| Autophagy induction as an efficient strategy to eradicate tumors. | 2008 Oct |
|
| Cyanogenesis of wild lima bean (Phaseolus lunatus L.) is an efficient direct defence in nature. | 2009 |
|
| 454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides. | 2009 Dec 2 |
|
| A straightforward method for the colorimetric detection of endogenous biological cyanide. | 2009 Nov 15 |
|
| Constituents and secondary metabolite natural products in fresh and deteriorated cassava roots. | 2010 Apr |
|
| Tri-trophic level impact of host plant linamarin and lotaustralin on Tetranychus urticae and its predator Phytoseiulus persimilis. | 2010 Dec |
|
| Cassava: an appraisal of its phytochemistry and its biotechnological prospects. | 2010 Dec |
|
| Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon. | 2010 Feb 25 |
|
| An efficient treatment for detoxification process of cassava starch by plant cell wall-degrading enzymes. | 2010 Jan |
|
| The retail market for fresh cassava root tubers in the European Union (EU): the case of Copenhagen, Denmark--a chemical food safety issue? | 2010 Jan 30 |
|
| The adenovirus-mediated linamarase/linamarin suicide system: a potential strategy for the treatment of hepatocellular carcinoma. | 2010 Mar 28 |
|
| The targets of acetone cyanohydrin neurotoxicity in the rat are not the ones expected in an animal model of konzo. | 2010 Mar-Apr |
|
| Genetic screening identifies cyanogenesis-deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism. | 2010 May |
|
| Naturally occurring food toxins. | 2010 Sep |
|
| Research into mercury exposure and health education in subsistence fish-eating communities of the Amazon basin: potential effects on public health policy. | 2010 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:48:58 UTC 2023
by
admin
on
Fri Dec 15 17:48:58 UTC 2023
|
| Record UNII |
H3V9RP3WLO
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
554-35-8
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
DTXSID8052857
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
H3V9RP3WLO
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
11128
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
16441
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
C005091
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
LINAMARIN
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | |||
|
m6822
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY | Merck Index | ||
|
3507
Created by
admin on Fri Dec 15 17:48:58 UTC 2023 , Edited by admin on Fri Dec 15 17:48:58 UTC 2023
|
PRIMARY |