DESMETHYLMISONIDAZOLE

OCC(O)CN1C=CN=C1[N+]([O-])=O

InChIKey=NUGLIYXAARVRPQ-UHFFFAOYSA-N

InChI=1S/C6H9N3O4/c10-4-5(11)3-8-2-1-7-6(8)9(12)13/h1-2,5,10-11H,3-4H2

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

PubMed

Title	Date	PubMed
The neurotoxicity of radiosensitizing drugs: a biochemical assessment of desmethylmisonidazole (DMM) in the rat.	1985-01	3918357
Oncogenic transformation systems involving mammalian cells in vitro to determine the relative risks of different treatment modalities.	1984-12	6515665
Activation of misonidazole by rat liver microsomes and purified NADPH-cytochrome c reductase.	1982-02-15	6802140
Structure-function dependence and allopurinol inhibition of radiosensitizer/nitroreductase interaction: approaches to improving therapeutic ratios.	1980	6771029
The mutagenic action of nitroimidazoles. II. Effects of 2-nitroimidazoles.	1975-06	1093016

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:35:51 GMT 2025` Edited by `admin` on `Mon Mar 31 17:35:51 GMT 2025`
Record UNII	H3N358OVQW
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

DESMETHYLMISONIDAZOLE

Common Name

English

NSC-261036

Preferred Name

English

RO-5-9963

Code

English

SR 1530

Code

English

RO 5-9963

Code

English

SR-1530

Code

English

1,2-PROPANEDIOL, 3-(2-NITRO-1H-IMIDAZOL-1-YL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C798