Details
Stereochemistry | ACHIRAL |
Molecular Formula | C8H12N4 |
Molecular Weight | 164.2077 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C1CN(CCN1)C2=NC=CC=N2
InChI
InChIKey=MRBFGEHILMYPTF-UHFFFAOYSA-N
InChI=1S/C8H12N4/c1-2-10-8(11-3-1)12-6-4-9-5-7-12/h1-3,9H,4-7H2
Molecular Formula | C8H12N4 |
Molecular Weight | 164.2077 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Pharmacokinetic-pharmacodynamic modeling of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in rats. | 2002 Dec |
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In vivo comparison of two 5-HT1A receptors agonists alnespirone (S-20499) and buspirone on locus coeruleus neuronal activity. | 2003 Jan 10 |
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A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model. | 2007 Sep 4 |
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Mass spectrometry analysis of phosphopeptides after peptide carboxy group derivatization. | 2008 Nov 1 |
|
Pharmacokinetic interaction between tandospirone and fluvoxamine in the rat contextual conditioned fear stress model and its functional consequence: Involvement of cytochrome P450 3A4. | 2008 Oct |
|
A new strategy for antidepressant prescription. | 2010 |
|
Synthesis and biological activity of some novel trifluoromethyl-substituted 1,2,4-triazole and bis(1,2,4-triazole) Mannich bases containing piperazine rings. | 2010 May 12 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:00:26 GMT 2025
by
admin
on
Mon Mar 31 18:00:26 GMT 2025
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Record UNII |
H3B5B38F56
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Record Status |
Validated (UNII)
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Record Version |
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Preferred Name | English | ||
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Systematic Name | English | ||
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Code System | Code | Type | Description | ||
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244-135-5
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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PRIMARY | |||
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1078573
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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Pyrimidinylpiperazine
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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88747
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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PRIMARY | |||
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H3B5B38F56
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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PRIMARY | |||
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20980-22-7
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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PRIMARY | |||
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DTXSID00864967
Created by
admin on Mon Mar 31 18:00:26 GMT 2025 , Edited by admin on Mon Mar 31 18:00:26 GMT 2025
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PRIMARY |
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TARGET -> INHIBITOR |
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SALT/SOLVATE -> PARENT |
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PARENT -> METABOLITE ACTIVE |
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Related Record | Type | Details | ||
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PARENT -> IMPURITY |
impurity detected at UV 240 nm
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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