FLUOTRACEN HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H24F3N.ClH
Molecular Weight	383.878
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.C[C@@H]1C2=C(C=CC=C2)[C@H](CCCN(C)C)C3=C1C=CC(=C3)C(F)(F)F

InChI

InChIKey=LUIRCXMGCSEASE-MQZJHDQISA-N

InChI=1S/C21H24F3N.ClH/c1-14-16-7-4-5-8-18(16)19(9-6-12-25(2)3)20-13-15(21(22,23)24)10-11-17(14)20;/h4-5,7-8,10-11,13-14,19H,6,9,12H2,1-3H3;1H/t14-,19+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C21H24F3N
Molecular Weight	347.4172
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9804284

Fluotracen (SKF-28,175) is a tricyclic drug which possesses dual antidepressant and antipsychotic activity mediated through blockage of GABA(A) receptors.

Approval Year

PubMed

Title	Date	PubMed
Fluotracen: a tricyclic compound with the combined properties of antidepressants and antipsychotics in animals.	1977	410422
Clinical experience with fluotracen HCL: report of a case.	1979	401008
Fluotracen (SKF 28, 175): a new antidepressant. Double-blind study with amitriptyline.	1980	6996019

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:46:57 UTC 2023` Edited by `admin` on `Fri Dec 15 16:46:57 UTC 2023`
Record UNII	H3998N6BXB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUOTRACEN HYDROCHLORIDE

Official Name

English

SK&F-28175

Code

English

(±)-CIS-9,10-DIHYDRO-N,N,10-TRIMETHYL-2-(TRIFLUOROMETHYL)-9-ANTHRACENEPROPYLAMINE HYDROCHLORIDE

Systematic Name

English

FLUOTRACEN HYDROCHLORIDE [USAN]

Common Name

English

FLUOTRACEN HYDROCHLORIDE [MART.]

Common Name

English

9-ANTHRACENEPROPANAMINE, 9,10-DIHYDRO-N,N,10-TRIMETHYL-2-(TRIFLUOROMETHYL)-, CIS-(±)-, HYDROCHLORIDE

Systematic Name

English

SK&F 28175

Code

English

FLUOTRACEN HCL

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2110950