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Details

Stereochemistry RACEMIC
Molecular Formula C21H24F3N.ClH
Molecular Weight 383.878
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUOTRACEN HYDROCHLORIDE

SMILES

Cl.C[C@@H]1C2=C(C=CC=C2)[C@H](CCCN(C)C)C3=C1C=CC(=C3)C(F)(F)F

InChI

InChIKey=LUIRCXMGCSEASE-MQZJHDQISA-N
InChI=1S/C21H24F3N.ClH/c1-14-16-7-4-5-8-18(16)19(9-6-12-25(2)3)20-13-15(21(22,23)24)10-11-17(14)20;/h4-5,7-8,10-11,13-14,19H,6,9,12H2,1-3H3;1H/t14-,19+;/m1./s1

HIDE SMILES / InChI

Molecular Formula C21H24F3N
Molecular Weight 347.4172
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Fluotracen (SKF-28,175) is a tricyclic drug which possesses dual antidepressant and antipsychotic activity mediated through blockage of GABA(A) receptors.

Approval Year

PubMed

PubMed

TitleDatePubMed
Fluotracen: a tricyclic compound with the combined properties of antidepressants and antipsychotics in animals.
1977
Clinical experience with fluotracen HCL: report of a case.
1979
Fluotracen (SKF 28, 175): a new antidepressant. Double-blind study with amitriptyline.
1980
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:46:57 GMT 2023
Edited
by admin
on Fri Dec 15 16:46:57 GMT 2023
Record UNII
H3998N6BXB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUOTRACEN HYDROCHLORIDE
MART.   USAN  
USAN  
Official Name English
SK&F-28175
Code English
(±)-CIS-9,10-DIHYDRO-N,N,10-TRIMETHYL-2-(TRIFLUOROMETHYL)-9-ANTHRACENEPROPYLAMINE HYDROCHLORIDE
Systematic Name English
FLUOTRACEN HYDROCHLORIDE [USAN]
Common Name English
FLUOTRACEN HYDROCHLORIDE [MART.]
Common Name English
9-ANTHRACENEPROPANAMINE, 9,10-DIHYDRO-N,N,10-TRIMETHYL-2-(TRIFLUOROMETHYL)-, CIS-(±)-, HYDROCHLORIDE
Systematic Name English
SK&F 28175
Code English
FLUOTRACEN HCL
Common Name English
Code System Code Type Description
ChEMBL
CHEMBL2110950
Created by admin on Fri Dec 15 16:46:57 GMT 2023 , Edited by admin on Fri Dec 15 16:46:57 GMT 2023
PRIMARY
PUBCHEM
76957620
Created by admin on Fri Dec 15 16:46:57 GMT 2023 , Edited by admin on Fri Dec 15 16:46:57 GMT 2023
PRIMARY
NCI_THESAURUS
C169992
Created by admin on Fri Dec 15 16:46:57 GMT 2023 , Edited by admin on Fri Dec 15 16:46:57 GMT 2023
PRIMARY
CAS
57363-14-1
Created by admin on Fri Dec 15 16:46:57 GMT 2023 , Edited by admin on Fri Dec 15 16:46:57 GMT 2023
PRIMARY
FDA UNII
H3998N6BXB
Created by admin on Fri Dec 15 16:46:57 GMT 2023 , Edited by admin on Fri Dec 15 16:46:57 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY