HEXAMETHYLDISILAZANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H19NSi2
Molecular Weight	161.3928
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[Si](C)(C)N[Si](C)(C)C

InChI

InChIKey=FFUAGWLWBBFQJT-UHFFFAOYSA-N

InChI=1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3

HIDE SMILES / InChI

Molecular Formula	C6H19NSi2
Molecular Weight	161.3928
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Bone is not essential for osteoclast activation.	2010-09-17	20862258
Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin.	2010-08-25	20666466
The pneumococcal serine-rich repeat protein is an intra-species bacterial adhesin that promotes bacterial aggregation in vivo and in biofilms.	2010-08-12	20714350
[Fe(4)S(4)](q) cubane clusters (q = 4+, 3+, 2+) with terminal amide ligands.	2010-07-19	20553035
Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles.	2010-05-15	20403703
Bis(N-triisopropyl-silyl-quinolin-8-aminato)nickel(II).	2009-12-04	21579956
Solid-state (49/47)Ti NMR of titanium-based MCM-41 hybrid materials.	2009-11-03	19810676
Reversible transformation of a stable monomeric silicon(II) compound into a stable disilene by phase transfer: experimental and theoretical studies of the system {[(Me3Si)2N](Me5C5)Si}n with n = 1,2.	2009-09-02	19655748
Synthesis, structure, and reactivity of low-coordinate 1,1,3,3-tetraethylguanidinate complexes.	2009-08-17	19624099
Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness.	2009-08-04	19603013
pH-responsive biodegradable micelles based on acid-labile polycarbonate hydrophobe: synthesis and triggered drug release.	2009-07-13	19469499
Beta-diketiminato calcium and magnesium amides; model complexes for hydroamination catalysis.	2009-05-18	19326917
Hydrofluoric-acid-resistant and hydrophobic pure-silica-zeolite MEL low-dielectric-constant films.	2009-05-05	19344154
Synthesis and characterization of group 11 1,1,3,3-tetraalkylguanidinate (TAG) clusters: [M2(mu-TAG){mu-N(SiMe3)2}]2 (M = Cu, Ag, and Au).	2009-03-16	19209913
Synthesis of an imprinted hybrid organic-inorganic polymeric sol-gel matrix toward the specific binding and isotherm kinetics investigation of creatinine.	2009-03-15	19236048
[μ-Bis(trimethyl-silyl)amido]bis-[μ-N,N-dimethyl-N',N''-bis-(trimethyl-silyl)guanidinato]-triangulo-tricopper(I).	2009-03-14	21582350
Synthesis and characterization of lithium hemiporphyrazines.	2009-02-16	19146413
Solution interaction of potassium and calcium bis(trimethylsilyl)amides; preparation of Ca[N(SiMe3)2]2 from dibenzylcalcium.	2009-02-16	19138130
An Ugi reaction in the total synthesis of (-)-dysibetaine.	2009	19173271
Mercury or silver atoms bridging trinuclear titanium imido-nitrido systems.	2008-12-28	19057779
Sequential and selective Buchwald-Hartwig amination reactions for the controlled functionalization of 6-bromo-2-chloroquinoline: synthesis of ligands for the Tec Src homology 3 domain.	2008-11-21	18950225
Silica passivation efficiency monitored by a surface-bound fluorescent dye.	2008-08-19	18616310
Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines.	2008-08-08	18691415
Ammonium benzene-phospho-nate.	2008-07-26	21203300
Surface property and in vitro biodegradation of microspheres fabricated by poly(epsilon-caprolactone-b-ethylene oxide) diblock copolymers.	2008-03-15	17647229
Reversibility in the protonolysis of a beta-diketiminate stabilised calcium bis(trimethylsilyl)amide with benzylamine.	2008-03-14	18305840
Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading.	2008	19011687
Zinc complexes of the biomimetic N,N,O ligand family of substituted 3,3-bis(1-alkylimidazol-2-yl)propionates: the formation of oxalate from pyruvate.	2007-11	17828423
Structure and reaction mechanism of basil eugenol synthase.	2007-10-03	17912370
A stable chiral diaminocyclopropenylidene.	2007-09-21	17728886
FeSO4 x 7H2O-catalyzed four-component synthesis of protected homoallylic amines.	2007-07-06	17550291
Efficient nucleophilic aromatic substitution between aryl nitrofluorides and alkynes.	2007-07-05	17552534
Synthesis and structural characterisation of lithium and sodium 2,6-dibenzylphenolate complexes.	2006-07-21	16820846
1,2-Eliminations in a novel reductive coupling of nitroarenes to give azoxy arenes by sodium bis(trimethylsilyl)amide.	2005-07-21	16018623
Base-promoted acyloin rearrangement of 1,8-di-tert-butyldimethylsilyloxybicyclo[2.2.2]oct-5-en-2-ones.	2005-06	15930779
C-H Activation (gamma-deprotonation) of a Sm(III) bis(trimethylsilyl)amide complex via macrocyclic stabilisation of the sodium counter ion.	2005-03-28	15770269
Unprecedented catalytic asymmetric reduction of N-H imines.	2005-01-20	15646996
The (Me5C5)Si+ cation: a stable derivative of HSi+.	2004-08-06	15232074
Determination of the absolute structure of (+)-cystothiazole B.	2004-06	15187406
Silylation reaction of dextran: effect of experimental conditions on silylation yield, regioselectivity, and chemical stability of silylated dextrans.	2003-09-10	12959617
Linear and cyclic polysilanes containing the bis(trimethylsilyl)amino group: synthesis, reactions, and spectroscopic characterization.	2003-07-28	12870947
Synthesis of 11C-amides using [11C]carbon monoxide and in situ activated amines by palladium-mediated carboxaminations.	2003-02-07	12926257
Structural studies of N,N'-di(ortho-fluorophenyl)formamidine group 1 metallation.	2003-01-20	12532290
Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity.	2002-10	12368443
Synthesis and characterization of endcapped C18 stationary phases using a silica hydride intermediate.	2002-02-22	11883653
Palladium-catalyzed synthesis of arylamines from aryl halides and lithium bis(trimethylsilyl)amide as an ammonia equivalent.	2001-08-23	11506620

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:12:33 GMT 2025` Edited by `admin` on `Mon Mar 31 19:12:33 GMT 2025`
Record UNII	H36C68P1BH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-93895

Preferred Name

English

HEXAMETHYLDISILAZANE

Systematic Name

English

HEXAMETHYLDISILAZANE [MI]

Common Name

English

HMDS

Common Name

English

1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE

Systematic Name

English

HEXAMETHYLDISILAZANE [HSDB]

Common Name

English

Code System Code Type Description

SMS_ID

100000170857