1,1-DIPHENYLUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H12N2O
Molecular Weight	212.2472
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)N(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=XKAFKUGMXFMRCC-UHFFFAOYSA-N

InChI=1S/C13H12N2O/c14-13(16)15(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,14,16)

HIDE SMILES / InChI

Molecular Formula	C13H12N2O
Molecular Weight	212.2472
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The X-ray crystal structure of 4-diphenylcarbamyl-N-methyl-piperidine methobromide (the carbamate analogue of 4-DAMP methiodide).	1989 Oct	2819329
Discovery of cell-permeable non-peptide inhibitors of beta-secretase by high-throughput docking and continuum electrostatics calculations.	2005 Aug 11	16078830
Silica-gel-confined ionic liquids: a new attempt for the development of supported nanoliquid catalysis.	2005 Sep 5	15997434
Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).	2006 Jan	16219910
Genetic instability in calamondin (Citrus madurensis Lour.) plants derived from somatic embryogenesis induced by diphenylurea derivatives.	2007 Aug	17333016
3,3'-Diphenyl-1,1'-[2,2'-oxybis(2,1-phenyl-ene)]diurea N,N-dimethyl-formamide disolvate.	2007 Dec 18	21200869
Synthesis and biological evaluation of benzoic acid derivatives as potent, orally active VLA-4 antagonists.	2007 Feb 15	17194595
Design of new plasmepsin inhibitors: a virtual high throughput screening approach on the EGEE grid.	2007 Sep-Oct	17727268
Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells.	2008	19096717
Pretreatment of wastewater containing a mixture of organic pollutants obtained from a CC2 plant by coagulation.	2008	18824806
Potent activation of large-conductance Ca2+-activated K+ channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) in pituitary tumor (GH3) cells.	2008 Dec	18809671
Identification of 4-[1-[3-chloro-4-[N'-(5-fluoro-2-methylphenyl)ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]benzoic acid as a potent, orally active VLA-4 antagonist.	2008 Dec 1	18952443
3-amino-benzo[d]isoxazoles as novel multitargeted inhibitors of receptor tyrosine kinases.	2008 Mar 13	18260617
Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.	2008 May	18452879
Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart.	2008 May	18005217
Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics.	2009 Aug 13	19572550
A novel and potent VLA-4 antagonist based on trans-4-substituted cyclohexanecarboxylic acid.	2009 Feb 1	19124247
[Monitoring the synthesis of N,N-diphenyl urea by IR-online].	2009 Jul	19798939
Suicide nucleophilic attack: reactions of benzohydroxamate anion with bis(2,4-dinitrophenyl) phosphate.	2009 Jul 17	19459594
Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function.	2009 Jul 3	19578543
Menthol increases human glioblastoma intracellular Ca2+, BK channel activity and cell migration.	2009 Sep 24	19778436
Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.	2010 Oct 15	20833055

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:25:20 GMT 2023` Edited by `admin` on `Fri Dec 15 17:25:20 GMT 2023`
Record UNII	H33D27I551
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,1-DIPHENYLUREA

Systematic Name

English

DIPHENYLUREA, 1,1-

Systematic Name

English

N,N-DIPHENYLUREA

Systematic Name

English

NSC-8715

Code

English

Code System Code Type Description

EPA CompTox

DTXSID7025184