CEPADACURSEN SODIUM

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 14:40:06 GMT 2023` Edited by `admin` on `Sat Dec 16 14:40:06 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	H31ZZO36P5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CEPADACURSEN SODIUM

Official Name

English

CIVI-007

Code

English

DNA, D(P-THIO)((2'-O,4'-C-METHYLENE)RA-(2'-O,4'-C-METHYLENE)RA-(2'-O,4'-C-METHYLENE)M5RU-G-C-T-A-C-A-A-A-A-(2'-O,4'-C-METHYLENE)RC-(2'-O,4'-C-METHYLENE)M5RC-(2'-O,4'-C-METHYLENE)M5RC-(2'-O,4'-C-METHYLENE)RA), 5'-(O-(6-((N2,N6-BIS(2-(2-(2-(2-((2-(ACETYLAM

Systematic Name

English

ALL-P-AMBO-5'-O-(26-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-11,14-BIS((4-(2-(2-(2-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)ETHOXY)ETHOXY)ETHOXY)ACETAMIDO)BUTYL)-1,10,13,16-TETRAOXO-1-SULFANYL-2,18,21,24,26-PENTAOXA-9,12,15-TRIAZA-

Common Name

English

CEPADACURSEN SODIUM [USAN]

Common Name

English

Code System Code Type Description

USAN

GH-58

Created by admin on Sat Dec 16 14:40:07 GMT 2023 , Edited by admin on Sat Dec 16 14:40:07 GMT 2023

PRIMARY

FDA UNII

H31ZZO36P5

Created by admin on Sat Dec 16 14:40:07 GMT 2023 , Edited by admin on Sat Dec 16 14:40:07 GMT 2023

PRIMARY

CAS

2252375-14-5

Created by admin on Sat Dec 16 14:40:07 GMT 2023 , Edited by admin on Sat Dec 16 14:40:07 GMT 2023

PRIMARY

NCI_THESAURUS

C180641

Created by admin on Sat Dec 16 14:40:07 GMT 2023 , Edited by admin on Sat Dec 16 14:40:07 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2,'4'-locked-Ribose (alpha-L-LNA)	1_1-1_3;1_14-1_16	6 / 16
Deoxyribose (DNA)	1_4-1_13	10 / 16

Linkage	Site Range	Site Count
Sodium Phosporothioate	1_2-1_16	15 / 15

Related Record Type Details


					UGH88FK62E

CEPADACURSEN

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE_SUBSTITUTION	[1_14] [1_15]	SITE_SPECIFIC			5-METHYL-2'-O,4'-C-METHYLENECYTIDINE	HH0X5P4HEO