METHOXPHENIDINE

COC1=CC=CC=C1C(CC2=CC=CC=C2)N3CCCCC3

InChIKey=QXXCUXIRBHSITD-UHFFFAOYSA-N

InChI=1S/C20H25NO/c1-22-20-13-7-6-12-18(20)19(21-14-8-3-9-15-21)16-17-10-4-2-5-11-17/h2,4-7,10-13,19H,3,8-9,14-16H2,1H3

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Targets

Primary Target	Pharmacology	Potency
Norepinephrine transporter 197 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29225192	Inhibitor 8504	7.8 µM [IC50]
Alpha-2a adrenergic receptor 70 Target ID: CHEMBL1867 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29225192	Binding Agent 1076	2.6 µM [Ki]
Serotonin 2a (5-HT2a) receptor 237 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29225192	Binding Agent 1076	8.2 µM [Ki]

PubMed

Title	Date	PubMed
Effects of the new psychoactive substances diclofensine, diphenidine, and methoxphenidine on monoaminergic systems.	2018-01-15	29225192
Methoxphenidine Use Disorder: First Case Notified to the French Addictovigilance Network.	2017-06	28272088
Severe rhabdomyolysis and acute kidney injury associated with methoxphenidine.	2016-06	27007750

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:45:51 GMT 2025` Edited by `admin` on `Mon Mar 31 23:45:51 GMT 2025`
Record UNII	H2W7A6GZGX
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2-MEO-DIPHENIDINE

Preferred Name

English

METHOXPHENIDINE

Common Name

English

METHOXYDIPHENIDINE

Common Name

English

PIPERIDINE, 1-(1-(2-METHOXYPHENYL)-2-PHENYLETHYL)-, (±)-

Systematic Name

English

MXP

Common Name

English

PIPERIDINE, 1-(1-(2-METHOXYPHENYL)-2-PHENYLETHYL)-

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA