U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Fri Dec 15 16:44:50 GMT 2023
Edited
by admin
on Fri Dec 15 16:44:50 GMT 2023
Source Materials Class ORGANISM
Source Materials Type BACTERIUM
Source Materials Parent
Part BACTERIAL CAPSULE
Fraction Name POLYSACCHARIDE ANTIGEN
Record UNII
H2W22AGF1P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NEISSERIA MENINGITIDIS GROUP C CAPSULAR OLIGOSACCHARIDE DIPHTHERIA CRM197 PROTEIN CONJUGATE ANTIGEN
Common Name English
Classification Tree Code System Code
NDF-RT N0000183895
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
Code System Code Type Description
NDF-RT
N0000183364
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
PRIMARY Actively Acquired Immunity [PE]
NDF-RT
N0000170916
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
PRIMARY Vaccines, Inactivated [Chemical/Ingredient]
DAILYMED
H2W22AGF1P
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
PRIMARY
FDA UNII
H2W22AGF1P
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
PRIMARY
DRUG BANK
DB14428
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
PRIMARY
NDF-RT
N0000170889
Created by admin on Fri Dec 15 16:44:50 GMT 2023 , Edited by admin on Fri Dec 15 16:44:50 GMT 2023
PRIMARY Meningococcal Vaccines [Chemical/Ingredient]
Related Record Type Details
TARGET ORGANISM->VACCINE ANTIGEN

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CONJUGATION CONJUGATION CONJUGATING AGENT ADIPIC ACID BIS(N-HYDROXYSUCCINIMIDE) ESTER W98WEU25G4
REDUCTION REDUCE END GROUPS REDUCING AGENT SODIUM BOROHYDRIDE 87L0B9CPPA
ACTIVATION FOR REDUCTIVE AMINATION ACTIVATION FOR REDUCTIVE AMINATION AMINATION AMMONIUM ACETATE RRE756S6Q2
PARTIAL HYDROLYSIS DEPOLYMERIZATION ACID TREATMENT Acetic acid Q40Q9N063P
CONJUGATION CONJUGATION PROTEIN CONJUGATE CORYNEBACTERIUM DIPHTHERIAE CRM197 PROTEIN 08VC9WC084

Physical Modifications

Modification Role Parameter Name Amount
MOLECULAR SIZING SIZING

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
PROTEIN CONJUGATION CORYNEBACTERIUM DIPHTHERIAE CRM197 PROTEIN 08VC9WC084
Name Property Type Amount Referenced Substance Defining Parameters References
POLYSACCHARIDE TO PROTEIN RATIO CHEMICAL
MOL_WEIGHT:WEIGHT AVERAGE CHEMICAL