Donzakimig

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:10:53 GMT 2023` Edited by `admin` on `Sat Dec 16 18:10:53 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY FUSION PROTEIN
Protein Sub Type
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	H239R928TY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Donzakimig

Official Name

English

Fused G1(VH-CH1-h)-scFv heavy-kappa heavy chain humanized (1-486) [G1(VH-CH1-h) anti-IL22 humanized (1-222) [VH (Homo sapiens IGHV3-23*04 (83.7%) -(IGHD) -IGHJ5*02 (100%), CDR-IMGT [8.7.13] (26-33.51-57.96-108)) (1-119) -Homo sapiens IGHG1*01 CH1-h, G1m1

Common Name

English

mmunoglobulin G1(VH-CH1-h)-scFv_L-kappa-scFv, anti-[Homo sapiens IL22 (interleukin 22, IL-22, ILTIF, IL-TIF)], anti-[Homo sapiens IL13 (interleukin 13, IL-13)] and anti-[Homo sapiens ALB (albumin, human serum albumin, HAS)], humanized, trispecific, triva

Common Name

English

donzakimig [INN]

Common Name

English

Immunoglobulin G1, anti-(human interleukin 22) (human-Oryctolagus cuniculus γ1-chain N-terminal fragment) fusion protein with peptide linker (SGGGGSGGGGS) fusion protein with immunoglobulin anti-(human serum albumin) (human-Oryctolagus cuniculus single-

Common Name

English

Code System Code Type Description

INN

12679

Created by admin on Sat Dec 16 18:10:53 GMT 2023 , Edited by admin on Sat Dec 16 18:10:53 GMT 2023

PRIMARY

FDA UNII

H239R928TY

Created by admin on Sat Dec 16 18:10:53 GMT 2023 , Edited by admin on Sat Dec 16 18:10:53 GMT 2023

PRIMARY

From	To
1_222	2_219
2_389	2_454
2_274	2_465
2_252	2_326
2_139	2_199
2_23	2_88
1_397	1_463
1_277	1_477
1_255	1_328
1_146	1_202
1_22	1_95

Related Record Type Details


					H239R928TY

Donzakimig

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL