Osemitamab

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:22:55 GMT 2023` Edited by `admin` on `Sat Dec 16 15:22:55 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	Humanized
Sequence Type	COMPLETE
Record UNII	H14V1A2F4D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Osemitamab

Official Name

English

TST001

Code

English

TST-001

Code

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (SFTPJ, surfactant associated protein J) isoform 2, extracellular domain 1 (EC1)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-46*01 (87.8%) -(IGHD) -IGHJ4

Common Name

English

TST 001 [WHO-DD]

Common Name

English

MSB-018

Code

English

osemitamab [INN]

Common Name

English

OSEMITAMAB [USAN]

Common Name

English

Immunoglobulin G1, anti-(human claudin 18.2) (human-Mus musculus monoclonal TST001 γ1-chain), disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

824721

Created by admin on Sat Dec 16 15:22:55 GMT 2023 , Edited by admin on Sat Dec 16 15:22:55 GMT 2023

Code System Code Type Description

FDA UNII

H14V1A2F4D

Created by admin on Sat Dec 16 15:22:55 GMT 2023 , Edited by admin on Sat Dec 16 15:22:55 GMT 2023

PRIMARY

CAS

2460539-61-9

Created by admin on Sat Dec 16 15:22:55 GMT 2023 , Edited by admin on Sat Dec 16 15:22:55 GMT 2023

PRIMARY

NCI_THESAURUS

C173726

Created by admin on Sat Dec 16 15:22:55 GMT 2023 , Edited by admin on Sat Dec 16 15:22:55 GMT 2023

PRIMARY

INN

11927

Created by admin on Sat Dec 16 15:22:55 GMT 2023 , Edited by admin on Sat Dec 16 15:22:55 GMT 2023

PRIMARY

USAN

LM-140

Created by admin on Sat Dec 16 15:22:55 GMT 2023 , Edited by admin on Sat Dec 16 15:22:55 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_145	2_201
2_221	4_220
2_262	2_322
1_145	1_201
2_368	2_426
3_23	3_94
3_140	3_200
4_23	4_94
4_140	4_200
1_221	3_220
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					H14V1A2F4D

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL