SOLASULFONE

Details

Stereochemistry	MIXED
Molecular Formula	C30H28N2O14S5.4Na
Molecular Weight	892.832
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)C(CC(C1=CC=CC=C1)S([O-])(=O)=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(NC(CC(C4=CC=CC=C4)S([O-])(=O)=O)S([O-])(=O)=O)C=C3

InChI

InChIKey=WAGUNVVOQBKLDL-UHFFFAOYSA-J

InChI=1S/C30H32N2O14S5.4Na/c33-47(34,25-15-11-23(12-16-25)31-29(50(41,42)43)19-27(48(35,36)37)21-7-3-1-4-8-21)26-17-13-24(14-18-26)32-30(51(44,45)46)20-28(49(38,39)40)22-9-5-2-6-10-22;;;;/h1-18,27-32H,19-20H2,(H,35,36,37)(H,38,39,40)(H,41,42,43)(H,44,45,46);;;;/q;4*+1/p-4

HIDE SMILES / InChI

Molecular Formula	C30H28N2O14S5
Molecular Weight	800.873
Charge	-4
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18864711 | https://www.ncbi.nlm.nih.gov/pubmed/18870128 | https://www.ncbi.nlm.nih.gov/pubmed/14784378 | https://www.ncbi.nlm.nih.gov/pubmed/18904721

Solasulfone (sulphetrone) was used in drug therapy of leprosy. It was also used in a chemotherapy of pulmonary tuberculosis. Sulphetrone has a low toxicity and an antituberculous efficiency approaching that of its parent compound, diaminodiphenylsulphone; it is also curative in infections due to beta-haemolytic streptococci.

Approval Year

PubMed

Title	Date	PubMed
[Comparative study of the antioxidant effect of solasulfone and alpha-tocopherol].	2000 Jan	10710627

Sample Use Guides

In Vivo Use Guide

Male rabbits: Suspension or solution by stomach tube or parenterally, in dose of 0.5 g/kg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:17:16 GMT 2023` Edited by `admin` on `Fri Dec 15 17:17:16 GMT 2023`
Record UNII	H12JE4313S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SOLASULFONE

Official Name

English

solasulfone [INN]

Common Name

English

TETRASODIUM SALT OF 1,1'-(SULFONYLBIS(P-PHENYLIMINO)BIS-(3-PHENYL-1,3-PROPANEDISULFONIC ACID)

Common Name

English

SOLASULFONE [MI]

Common Name

English

SULFETRONE

Common Name

English

SOLASULPHONE

Common Name

English

SOLAPSONE [MART.]

Common Name

English

SOLAPSONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29739