ICOSPIRAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H31F2N5O2
Molecular Weight	507.5748
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)CN1CN(C2=CC=C(F)C=C2)C3(CCN(CC3)[C@H]4CC[C@](CC4)(C#N)C5=CC=C(F)C=C5)C1=O

InChI

InChIKey=HVWIHGNIDIIREZ-JIBACQESSA-N

InChI=1S/C28H31F2N5O2/c29-21-3-1-20(2-4-21)27(18-31)11-9-23(10-12-27)33-15-13-28(14-16-33)26(37)34(17-25(32)36)19-35(28)24-7-5-22(30)6-8-24/h1-8,23H,9-17,19H2,(H2,32,36)/t23-,27-

HIDE SMILES / InChI

Molecular Formula	C28H31F2N5O2
Molecular Weight	507.5748
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Ganellin C.R., Triggle David J., Dictionary of Pharmacological Agents retrieved from: https://books.google.ru/books?id=Z_mfTTIApVEC&pg=PA580&lpg=PA580&dq=ICOSPIRAMIDE+antiemetic&source=bl&ots=EtFOIrRJw1&sig=ACfU3U1uFj2IOf3ppgTb6FDwcaSf40NEtg&hl=ru&sa=X&ved=2ahUKEwjt07iFu77iAhXksosKHZ1KCNUQ6AEwCHoECAkQAQ#v=onepage&q=ICOSPIRAMIDE%20antiemetic&f=false

Icospiramide was developed as an antiemetic agent that has never been marketed.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:37:54 GMT 2023` Edited by `admin` on `Fri Dec 15 15:37:54 GMT 2023`
Record UNII	H0N246YG4Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ICOSPIRAMIDE

Official Name

English

icospiramide [INN]

Common Name

English

8-(CIS-4-CYANO-4-(P-FLUOROPHENYL)CYCLOHEXYL)-1-(P-FLUOROPHENYL)-4-OXO-1,3,8-TRIAZASPIRO(4.5)DECANE-3-ACETAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C267