U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:03:37 GMT 2023
Edited
by admin
on Sat Dec 16 12:03:37 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
GX4RN38YCG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 5
Common Name English
P-GLYCOPROTEIN ABCB5
Common Name English
ABCB5 P-GP
Common Name English
ABCB5
Common Name English
ABCB-5
Common Name English
Code System Code Type Description
FDA UNII
GX4RN38YCG
Created by admin on Sat Dec 16 12:03:37 GMT 2023 , Edited by admin on Sat Dec 16 12:03:37 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_17
N 1_85
N 1_91
N 1_371
N 1_390
N 1_423
N 1_789
N 1_819
N 1_910
N 1_1104
N 1_1188
Related Record Type Details
SUBSTRATE -> TRANSPORTER
Down-regulation of ABCB5αresulted in a gain of drug sensitivity to camptothecin 10-OH, 5-fluorouracil, and mitoxantrone.
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
Down-regulation of ABCB5αresulted in a gain of drug sensitivity to camptothecin 10-OH, 5-fluorouracil, and mitoxantrone.
SUBSTRATE -> TRANSPORTER
Responsible for the resistance to doxorubicin of a subset of malignant melanomas.
SUBSTRATE -> TRANSPORTER
Down-regulation of ABCB5αresulted in a gain of drug sensitivity to camptothecin 10-OH, 5-fluorouracil, and mitoxantrone.
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL