U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Wed Apr 02 19:48:55 GMT 2025
Edited
by admin
on Wed Apr 02 19:48:55 GMT 2025
Protein Type PEPTIDE
Protein Sub Type T-CELL ANTIGEN
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
GW9836P652
Record Status FAILED
Record Version
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Name Type Language
Leu-Thr-Asp-Leu-Gln-Pro-Tyr-Met-Arg-Glu-Phe-Val-Ala-His-Leu
Preferred Name English
HUMAN TELOMERASE REVERSE TRANSCRIPTASE PEPTIDE P766
Common Name English
hTERT (766-780 Q775E)
Common Name English
Code System Code Type Description
FDA UNII
GW9836P652
Created by admin on Wed Apr 02 19:48:55 GMT 2025 , Edited by admin on Wed Apr 02 19:48:55 GMT 2025
PRIMARY
Related Record Type Details
TARGET->VACCINE ANTIGEN
Cancer vaccine regimen combining human telomerase reverse transcriptase (hTERT) peptides with concomitant therapies targeting regulatory T cells (Tregs) and cyclooxygenase-2 (COX2)-mediated immunosuppression.
Related Record Type Details
ACTIVE MOIETY
primary objective was determination of the safety and tolerability of this combination therapy, with anti-cancer activity, immune response and detection of antigen-specific T cells as additional endpoints.
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL