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Details

Stereochemistry ACHIRAL
Molecular Formula C14H19NO2.BrH
Molecular Weight 314.218
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORMEPERIDINE HYDROBROMIDE

SMILES

Br.CCOC(=O)C1(CCNCC1)C2=CC=CC=C2

InChI

InChIKey=VWUBXYBLJBUKCC-UHFFFAOYSA-N
InChI=1S/C14H19NO2.BrH/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12;/h3-7,15H,2,8-11H2,1H3;1H

HIDE SMILES / InChI

Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C14H19NO2
Molecular Weight 233.3062
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Cerebellar and oculomotor dysfunction induced by rapid infusion of pethidine.
2014-03-11
Role of active metabolites in the use of opioids.
2009-02
Seizures in an Alzheimer's disease patient as a complication of colonoscopy premedication with meperidine.
2008-01
Detection of methylphenidate in the hair of children treated with Ritalin.
2007-12-21
Meperidine and skin surface warming additively reduce the shivering threshold: a volunteer study.
2007
CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
2004-09
Seizures due to norpethidine toxicity.
2000-08
Successful treatment of normeperidine neurotoxicity by hemodialysis.
2000-01
Norpethidine accumulation and generalized seizure during pethidine patient-controlled analgesia.
1999-06
Toxicity of norpethidine in sickle cell crisis.
1992-06-06
Normeperidine-induced seizures in hereditary coproporphyria.
1990-11
Normorphine, a neurotoxic metabolite?
1990-03-24
Norpethidine induced myoclonus in a patient with renal failure.
1989-12
Possible roles of normeperidine and hyponatremia in a postoperative death.
1987-11-15
Normeperidine toxicity.
1986-05
Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer.
1977-06
Patents

Patents

Substance Class Chemical
Created
by admin
on Tue Apr 01 16:26:38 GMT 2025
Edited
by admin
on Tue Apr 01 16:26:38 GMT 2025
Record UNII
GT98GPM2FY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORPETHIDINE HYDROBROMIDE
Preferred Name English
NORMEPERIDINE HYDROBROMIDE
Common Name English
PETHIDINE INTERMEDIATE B HYDROBROMIDE
Common Name English
4-PIPERIDINECARBOXYLIC ACID, 4-PHENYL-, ETHYL ESTER, HYDROBROMIDE (1:1)
Systematic Name English
ETHYL 4-PHENYL-4-PIPERIDINE-CARBOXYLATE HYDROBROMIDE
Systematic Name English
Code System Code Type Description
CAS
227470-64-6
Created by admin on Tue Apr 01 16:26:38 GMT 2025 , Edited by admin on Tue Apr 01 16:26:38 GMT 2025
PRIMARY
PUBCHEM
18794171
Created by admin on Tue Apr 01 16:26:38 GMT 2025 , Edited by admin on Tue Apr 01 16:26:38 GMT 2025
PRIMARY
FDA UNII
GT98GPM2FY
Created by admin on Tue Apr 01 16:26:38 GMT 2025 , Edited by admin on Tue Apr 01 16:26:38 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY