Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H12NO3S.H4N |
Molecular Weight | 316.375 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[NH4+].[O-]S(=O)(=O)C1=CC=CC2=CC=CC(NC3=CC=CC=C3)=C12
InChI
InChIKey=IPBNQYLKHUNLQE-UHFFFAOYSA-N
InChI=1S/C16H13NO3S.H3N/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;/h1-11,17H,(H,18,19,20);1H3
Molecular Formula | H3N |
Molecular Weight | 17.0305 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C16H13NO3S |
Molecular Weight | 299.344 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL3194 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19954984 |
1.1 µM [Kd] |
PubMed
Title | Date | PubMed |
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Folding pathway for partially folded rabbit muscle creatine kinase. | 2001 |
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The nuclear matrix is a thermolabile cellular structure. | 2001 Apr |
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Characteristics of sarcoplasmic reticulum membrane preparations isolated from skeletal muscles of active and hibernating ground squirrel Spermophilus undulatus. | 2001 Aug |
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Multiple unfolding intermediates of human placental alkaline phosphatase in equilibrium urea denaturation. | 2001 Dec |
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Role of the disulfide cleavage induced molten globule state of type a botulinum neurotoxin in its endopeptidase activity. | 2001 Dec 18 |
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The cytochrome c fold can be attained from a compact apo state by occupancy of a nascent heme binding site. | 2001 Dec 7 |
|
Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro. | 2001 Dec 7 |
|
Use of reversible denaturation for adsorptive immobilization of urease. | 2001 Jun |
|
Molecular mechanism for osmolyte protection of creatine kinase against guanidine denaturation. | 2001 Nov |
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Reversible changes of the wheat gamma 46 gliadin conformation submitted to high pressures and temperatures. | 2001 Nov |
|
Octyl glucoside induced formation of the molten globule-like state of glutamate dehydrogenase. | 2001 Nov |
|
Interaction of gramicidin with lysophosphatidylcholine as revealed by calorimetry and fluorescence spectroscopy. | 2001 Nov |
|
Tryptophan mutants of intestinal fatty acid-binding protein: ultraviolet absorption and circular dichroism studies. | 2001 Nov 15 |
|
Binding affinity properties of dendritic glycosides based on a beta-cyclodextrin core toward guest molecules and concanavalin A. | 2001 Nov 16 |
|
Acid-induced partly folded conformation resembling a molten globule state of xylanase from an alkalothermophilic Bacillus sp. | 2001 Nov 16 |
|
Conformational and functional significance of residue proline 17 in chicken muscle adenylate kinase. | 2001 Nov 23 |
|
Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations. | 2001 Nov 23 |
|
Partially folded conformations in the folding pathway of bovine carbonic anhydrase II: a fluorescence spectroscopic analysis. | 2001 Nov 5 |
|
Inactivation of NADP(+)-dependent isocitrate dehydrogenase by reactive oxygen species. | 2001 Nov-Dec |
|
Artificial chaperone mediated refolding of xylanase from an alkalophilic thermophilic Bacillus sp. Implications for in vitro protein renaturation via a folding intermediate. | 2001 Oct |
|
Hydrophobicity of whey protein concentrates measured by fluorescence quenching and its relation with surface functional properties. | 2001 Oct |
|
Structural changes in natural actomyosin and surimi from ling cod (Ophiodon elongatus) during frozen storage in the absence or presence of cryoprotectants. | 2001 Oct |
|
A partially folded intermediate conformation is induced in pectate lyase C by the addition of 8-anilino-1-naphthalenesulfonate (ANS). | 2001 Oct |
|
Effects of the antiplatelet agent TA-993 and its metabolite MB3 on the hemorheological properties of rat and human erythrocytes. | 2001 Oct 15 |
|
Clusterin, a binding protein with a molten globule-like region. | 2001 Oct 2 |
|
A role for aromatic amino acids in the binding of Xenopus ribosomal protein L5 to 5S rRNA. | 2001 Oct 23 |
|
Capture of a dimeric intermediate during transthyretin amyloid formation. | 2001 Oct 26 |
|
Resonance energy transfer study of peptide-lipid complexes. | 2001 Sep 18 |
|
Temperature-induced formation of a non-native intermediate state of the all beta-sheet protein CD2. | 2002 |
|
The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea. | 2002 Apr |
|
Thermodynamics of the ligandin function of human class Alpha glutathione transferase A1-1: energetics of organic anion ligand binding. | 2002 Apr 15 |
|
Adsorptive immobilization of intestinal brush border membrane on Triton X-100-substituted Sepharose 4B. | 2002 Feb |
|
Testing of the portal hypothesis: analysis of a V32G, F57G, K58G mutant of the fatty acid binding protein of the murine adipocyte. | 2002 Feb 12 |
|
Dendritic galactosides based on a beta-cyclodextrin core for the construction of site-specific molecular delivery systems: synthesis and molecular recognition studies. | 2002 Feb 15 |
|
Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin. | 2002 Feb 27 |
|
Highly divergent dihydrofolate reductases conserve complex folding mechanisms. | 2002 Jan 11 |
|
Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites. | 2002 Jan 15 |
|
The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin. | 2002 Jan 8 |
|
Converting troponin C into calmodulin: effects of mutations in the central helix and of changes in temperature. | 2002 Jun |
|
Urea-induced unfolding studies of free- and ligand-bound tetrameric ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Influence of quaternary structure on protein conformational stability. | 2002 Jun |
|
Pathway complexity of prion protein assembly into amyloid. | 2002 Jun 14 |
|
The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands. | 2002 Jun 28 |
|
Probing reactive center loop insertion in serpins: a simple method for ovalbumin. | 2002 Mar 1 |
|
Amyloid fibril formation of the mouse V(L) domain at acidic pH. | 2002 Mar 12 |
|
Oligomerization process of the hemolytic lectin CEL-III purified from a sea cucumber, Cucumaria echinata. | 2002 May |
|
Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis--potentially implicated mechanisms. | 2002 May |
|
Role of individual disulfide bonds in hen lysozyme early folding steps. | 2002 May |
|
Methionine oxidation as a major cause of the functional impairment of oxidized actin. | 2002 May 1 |
|
Guanidinium chloride induced unfolding of a hemocyanin subunit from Carcinus aestuarii. I. Apo form. | 2002 May 20 |
|
Amyloid-like fibril formation in an all beta-barrel protein involves the formation of partially structured intermediate(s). | 2002 May 24 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 07:51:15 GMT 2023
by
admin
on
Sat Dec 16 07:51:15 GMT 2023
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Record UNII |
GT7MN8DKD7
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Record Status |
Validated (UNII)
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120066
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m1924
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249-265-6
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Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |