Lumrotatug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 20:07:16 GMT 2023` Edited by `admin` on `Sat Dec 16 20:07:16 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	GT2R696LEM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Lumrotatug

Official Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1)], humanized monoclonal antibody

Common Name

English

lumrotatug [INN]

Common Name

English

Gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV4-4*08 (83.5%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-57.96-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1R120 (216) (120-217), hinge 1-15 (218-232),

Common Name

English

CM313

Common Name

English

Immunoglobulin G1, anti-(human ADP-ribosyl cyclase 1) (human-Mus musculus monoclonal CM313 γ1-chain), disulfide with human-Mus musculus monoclonal CM313 κ-chain, dimer

Common Name

English

CM-313

Common Name

English

Code System Code Type Description

INN

12639

Created by admin on Sat Dec 16 20:07:16 GMT 2023 , Edited by admin on Sat Dec 16 20:07:16 GMT 2023

PRIMARY

CAS

2760318-99-6

Created by admin on Sat Dec 16 20:07:16 GMT 2023 , Edited by admin on Sat Dec 16 20:07:16 GMT 2023

PRIMARY

FDA UNII

GT2R696LEM

Created by admin on Sat Dec 16 20:07:16 GMT 2023 , Edited by admin on Sat Dec 16 20:07:16 GMT 2023

PRIMARY

From	To
1_22	1_95
2_22	2_95
2_146	2_202
2_222	4_214
2_263	2_323
1_146	1_202
2_369	2_427
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_222	3_214
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					JMN849I3XV

ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1

TARGET->LIGAND

Amount:

Related Record Type Details


					GT2R696LEM

Lumrotatug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL