Imneskibart

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 16:01:04 GMT 2025` Edited by `admin` on `Wed Apr 02 16:01:04 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	GS5BXY84ZU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Imneskibart

Official Name

English

AU-007

Preferred Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens IL2 (interleukin 2)], Homo sapiens antibody; gamma1 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV1-24*01 (84.5%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapien

Common Name

English

Immunoglobulin G1 [238-alanine,239-alanine], anti-(human interleukin 2) (human monoclonal AU-007 ?1-chain), disulfide with human monoclonal AU-007 ?-chain, dimer

Common Name

English

AU007

Code

English

IMNESKIBART [USAN]

Common Name

English

Code System Code Type Description

USAN

LM-225

Created by admin on Wed Apr 02 16:01:04 GMT 2025 , Edited by admin on Wed Apr 02 16:01:04 GMT 2025

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SMS_ID

300000054724

Created by admin on Wed Apr 02 16:01:04 GMT 2025 , Edited by admin on Wed Apr 02 16:01:04 GMT 2025

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INN

13202

Created by admin on Wed Apr 02 16:01:04 GMT 2025 , Edited by admin on Wed Apr 02 16:01:04 GMT 2025

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NCI_THESAURUS

C187110

Created by admin on Wed Apr 02 16:01:04 GMT 2025 , Edited by admin on Wed Apr 02 16:01:04 GMT 2025

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FDA UNII

GS5BXY84ZU

Created by admin on Wed Apr 02 16:01:04 GMT 2025 , Edited by admin on Wed Apr 02 16:01:04 GMT 2025

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CAS

2919583-43-8

Created by admin on Wed Apr 02 16:01:04 GMT 2025 , Edited by admin on Wed Apr 02 16:01:04 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_148	2_204
2_224	4_220
2_265	2_325
1_148	1_204
2_371	2_429
3_23	3_94
3_140	3_200
4_23	4_94
4_140	4_200
1_224	3_220
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					GS5BXY84ZU

ACTIVE MOIETY

Interaction Type:

IN-VITRO

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_451] [2_451]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL