E3 ubiquitin-protein ligase CBL-B

Substance Class	Protein Created by `admin` on `Wed Apr 02 14:28:37 GMT 2025` Edited by `admin` on `Wed Apr 02 14:28:37 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	GQ9892W4JH
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

Casitas B-lineage lymphoma proto-oncogene b

Preferred Name

English

Signal transduction protein CBL-B

Common Name

English

RING finger protein 56

Common Name

English

SH3-binding protein CBL-B

Common Name

English

RING-type E3 ubiquitin transferase CBL-B

Common Name

English

Code System Code Type Description

FDA UNII

GQ9892W4JH

Created by admin on Wed Apr 02 14:28:37 GMT 2025 , Edited by admin on Wed Apr 02 14:28:37 GMT 2025

PRIMARY

Related Record Type Details


					Y9AV5Y4VQ4

INHIBITOR -> TARGET

Interaction Type:

PRECLINICAL

Amount:

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_363] [1_665] [1_709] [1_889]				TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO_ACID_SUBSTITUTION	[1_282] [1_476] [1_480] [1_484] [1_521] [1_525] [1_529] [1_634]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL