ALANINAMIDE, L-

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C3H8N2O
Molecular Weight	88.1084
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](N)C(N)=O

InChI

InChIKey=HQMLIDZJXVVKCW-REOHCLBHSA-N

InChI=1S/C3H8N2O/c1-2(4)3(5)6/h2H,4H2,1H3,(H2,5,6)/t2-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C3H8N2O
Molecular Weight	88.1084
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Neurokinin 1 receptor 35 Target ID: CHEMBL249 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7686493\|https://www.ncbi.nlm.nih.gov/pubmed/1282073\|https://www.ncbi.nlm.nih.gov/pubmed/8630576	Antagonist 2849		0.72 nM [IC50]

PubMed

Title	Date	PubMed
Efficient synthesis of a small molecule, nonpeptide inhibitor of LFA-1.	2010-10-01	20831178
Complete genome sequence of Marinobacter adhaerens type strain (HP15), a diatom-interacting marine microorganism.	2010-09-28	21304739
Ochrobactrum ciceri sp. nov., isolated from nodules of Cicer arietinum.	2010-07	19684324
Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras.	2010-05	19629638
Complete genome sequence of Gordonia bronchialis type strain (3410).	2010-01-28	21304674
Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.	2009-08	19468860
Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.	2008-12-25	19105725
Sugar-driven prebiotic synthesis of 3,5(6)-dimethylpyrazin-2-one: a possible nucleobase of a primitive replication process.	2008-08	18581252
Pseudoxanthobacter soli gen. nov., sp. nov., a nitrogen-fixing alphaproteobacterium isolated from soil.	2008-07	18599697
Complexes of Cu(II) ions and noncovalent interactions in systems with L-aspartic acid and cytidine-5'-monophosphate.	2008	18682818
Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats.	2007-09	17679773
Bacillus decisifrondis sp. nov., isolated from soil underlying decaying leaf foliage.	2007-05	17473244
Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs.	2006-12-01	16982190
Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.	2006-08	16644903
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors.	2006-07-15	16697194
[The effect of betulonic acid and its alanine amide derivatives on rat liver parenchyma repair during postcytostatic period].	2006-01-13	16405036
Purification, characterization, gene cloning and nucleotide sequencing of D: -stereospecific amino acid amidase from soil bacterium: Delftia acidovorans.	2005-12	15959727
Application of Fourier transform infrared spectroscopy for monitoring hydrolysis and synthesis reactions catalyzed by a recombinant amidase.	2005-11-01	16185648
Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.	2005-09	16099101
Effect of betulonic acid and its derivative [3-oxo-20(29)-lupene-28-oyl]-3-aminopropionic acid on liver structure in mice with RLS lymphoma.	2005-09	16307059
Single peptide bonds exhibit poly(pro)II ("random coil") circular dichroism spectra.	2005-07-13	15998070
Ion transfer at nanointerfaces between water and neat organic solvents.	2005-06-22	15954756
Visual enantiomeric recognition of amino acid derivatives in protic solvents.	2005-06-10	15932296
Dynamic kinetic resolution of amino acid amide catalyzed by D-aminopeptidase and alpha-amino-epsilon-caprolactam racemase.	2005-06-01	15913357
A DmpA-homologous protein from Pseudomonas sp. is a dipeptidase specific for beta-alanyl dipeptides.	2005-06	15955066
Quantitation of 3-aminopropionamide in potatoes-a minor but potent precursor in acrylamide formation.	2004-07-28	15264910
Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations.	2004-07-15	15239667
S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase.	2004-04	15066172
Design of chiral monochloro-s-triazine reagents for the liquid chromatographic separation of amino acid enantiomers.	2003-05-23	12862373
Chemically modified "polar patch" mutants of subtilisin in peptide synthesis with remarkably broad substrate acceptance: designing combinatorial biocatalysts.	2002-09-16	12298003
Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.	2002-05	11937780
Chemically modified chiral monolithic silica column prepared by a sol-gel process for enantiomeric separation by micro high-performance liquid chromatography.	2002-01-04	11822400
Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice.	1997-08	9308027
A neurokinin 1-receptor antagonist improves exercise-induced airway narrowing in asthmatic patients.	1996-03	8630576
'Sensory-efferent' neural control of mucus secretion: characterization using tachykinin receptor antagonists in ferret trachea in vitro.	1994-12	7889271

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:57:55 GMT 2025` Edited by `admin` on `Mon Mar 31 19:57:55 GMT 2025`
Record UNII	GOD06L4T27
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALANINE AMIDE

Preferred Name

English

ALANINAMIDE, L-

Systematic Name

English

(S)-(+)-2-AMINOPROPANAMIDE

Systematic Name

English

L-ALANINAMIDE

Systematic Name

English

PROPANAMIDE, 2-AMINO-, (S)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

444939