METHANIAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9N3O4S
Molecular Weight	231.229
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(=O)(=O)CNNC(=O)C1=CC=NC=C1

InChI

InChIKey=GQZQCROBCYNTMU-UHFFFAOYSA-N

InChI=1S/C7H9N3O4S/c11-7(6-1-3-8-4-2-6)10-9-5-15(12,13)14/h1-4,9H,5H2,(H,10,11)(H,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C7H9N3O4S
Molecular Weight	231.229
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://link.springer.com/chapter/10.1007/978-94-011-4439-1_12
Curator's Comment: Description was created based on several sources, including http://www.reference.md/files/C061/mC061382.html

Methaniazide (metaniazide) is the methanesulfonate derivative of isoniazid with antibacterial properties. It is used used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pulmonary tuberculosis 17 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13903641	Primary		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
[A case of tuberculous pleurisy associated with myoclonus and Quincke's edema due to isoniazid and isoniazid sodium methanesulfonate].	1989 Jun	2796112

Patents

Sample Use Guides

In Vivo Use Guide

600 mg/day

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:46:11 GMT 2023` Edited by `admin` on `Fri Dec 15 15:46:11 GMT 2023`
Record UNII	GN8S7ZES0F
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

METHANIAZIDE

Official Name

English

Methaniazide [WHO-DD]

Common Name

English

METHANIAZIDE [MART.]

Common Name

English

ISONICOTINIC ACID 2-(SULFOMETHYL)HYDRAZINE

Systematic Name

English

4-PYRIDINECARBOXYLIC ACID 2-(SULFOMETHYL)HYDRAZIDE

Common Name

English

methaniazide [INN]

Common Name

English

ISONIAZID METHANESULFONATE

Common Name

English

ISONIAZID METHANESULFONATE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C280