U.S. Department of Health & Human Services
National Institutes of Health
NCATS
Return Home
Inxight
Drugs
Search Substances
Home
Browse Drugs
US Approved Drugs
Marketed Drugs
Investigational Drugs
All Substances
Search
Structure Search
Sequence Search
Downloads
About
Search Substances
Nemolizumab
GN465U8B72
US Approved Rx (2024)
First approved in 2024
General
Record Details
Names
9
Identifiers
7
Subunits
4
Disulfide Links
16
Glycosylation
2
Relationships
1
Active Moiety
1
Characteristic Attributes
2
Nemolizumab
GN465U8B72
US Approved Rx (2024)
First approved in 2024
General
Approval Year
2024
52
Record Details
Substance Class
Protein
Protein Type
MONOCLONAL ANTIBODY
Protein Sub Type
IGG2
Sequence Origin
HUMANIZED MOUSE
Sequence Type
COMPLETE
Record UNII
GN465U8B72
Record Status
Validated (UNII)
Record Version
17
16
15
14
13
12
11
10
9
8
7
6
5
4
3
2
1
Names
9
Show
5
20
100
All
entries
Name
Type
Language
Name
Type
Language
Nemolizumab
Official Name
English
NEMOLIZUMAB [USAN]
Common Name
English
immunoglobulin G2-kappa, anti-[Homo sapiens IL31RA (interleukin 31 receptor subunit alpha)], humanized monoclonal antibody gamma2 heavy chain (1-445) [humanized VH (Homo sapiens IGHV1-2*02 (83.70%) -(IGHD)-IGHJ5*01) [8.8.14] (1-121) -Homo sapiens IGHG2*0
Common Name
English
CIM-331
Code
English
NEMOLIZUMAB [JAN]
Common Name
English
Showing 1 to 5 of 9 entries
Previous
1
2
Next
Identifiers
7
Show
5
20
100
All
entries
Code System
Code
Type
Description
Code System
Code
Type
Description
CAS
1476039-58-3
PRIMARY
FDA UNII
GN465U8B72
PRIMARY
WIKIPEDIA
Nemolizumab
PRIMARY
DRUG BANK
DB15252
PRIMARY
INN
10064
PRIMARY
Showing 1 to 5 of 7 entries
Previous
1
2
Next
Subunits
4
Disulfide Links
16
Show
5
20
100
All
entries
From
To
From
To
1_22
1_96
1_148
1_204
1_261
1_321
1_367
1_425
2_22
2_96
Showing 1 to 5 of 16 entries
Previous
1
2
3
4
Next
Glycosylation
2
Glycosylation Type
MAMMALIAN
Show
5
20
100
All
entries
Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_297
N
2_297
Showing 1 to 2 of 2 entries
Previous
1
Next
Relationships
1
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
3JW47OGM6P
INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA
TARGET -> INHIBITOR
Amount:
Showing 1 to 1 of 1 entries
Previous
1
Next
Active Moiety
1
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
GN465U8B72
Nemolizumab
ACTIVE MOIETY
Amount:
Showing 1 to 1 of 1 entries
Previous
1
Next
Characteristic Attributes
2
Show
5
20
100
All
entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 144000 Da (average)
Molecular Formula
CHEMICAL
ESTIMATED
C6384H9796N1678O2034S48
Showing 1 to 2 of 2 entries
Previous
1
Next
