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TRALOKINUMAB
GK1LYB375A
US Approved Rx (2021)
First approved in 2021
General
Record Details
Names
7
Classification
3
Identifiers
11
Subunits
4
Disulfide Links
15
Glycosylation
2
Relationships
1
Active Moiety
1
Characteristic Attributes
2
TRALOKINUMAB
GK1LYB375A
US Approved Rx (2021)
First approved in 2021
General
Approval Year
2021
470
Record Details
Substance Class
Protein
Protein Type
MONOCLONAL ANTIBODY
Protein Sub Type
IGG4
Sequence Origin
HUMAN
Sequence Type
COMPLETE
Record UNII
GK1LYB375A
Record Status
Validated (UNII)
Record Version
23
22
21
20
19
18
17
16
15
14
13
12
11
10
9
8
7
6
5
4
3
2
1
Names
7
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entries
Name
Type
Language
Name
Type
Language
TRALOKINUMAB
Official Name
English
TRALOKINUMAB [JAN]
Common Name
English
TRALOKINUMAB [USAN]
Common Name
English
CAT-354
Code
English
Tralokinumab [WHO-DD]
Common Name
English
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2
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Classification
3
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Designated/Withdrawn
ORPHAN DRUG
Designated/Withdrawn
Treatment of idiopathic pulmonary fibrosis
FDA ORPHAN DRUG
373812
Withdrawn
EU ORPHAN DRUG
Withdrawn
Treatment of idiopathic pulmonary fibrosis
EU-Orphan Drug
EU/3/12/1061
Biological Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Monoclonal Antibody
NCI_THESAURUS
C20401
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Identifiers
11
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Code System
Code
Type
Description
Code System
Code
Type
Description
SMS_ID
100000175358
PRIMARY
WIKIPEDIA
TRALOKINUMAB
PRIMARY
FDA UNII
GK1LYB375A
PRIMARY
ChEMBL
CHEMBL1743081
PRIMARY
DAILYMED
GK1LYB375A
PRIMARY
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1
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3
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Subunits
4
Disulfide Links
15
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entries
From
To
From
To
1_22
1_96
1_136
3_213
1_149
1_205
1_228
2_228
1_231
2_231
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1
2
3
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Glycosylation
2
Glycosylation Type
MAMMALIAN
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_299
N
2_299
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1
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Relationships
1
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entries
Related Record
Type
Details
Related Record
Type
Details
JC88P1P6QM
HUMAN INTERLEUKIN 13
TARGET -> INHIBITOR
Interaction Type:
BINDING
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Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
GK1LYB375A
TRALOKINUMAB
ACTIVE MOIETY
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:ESTIMATE
CHEMICAL
ESTIMATE 147000 AMU (average)
Molecular Formula
CHEMICAL
ESTIMATED
C6386H9822N1702O2016S44
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