Surabgene Lomparvovec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 03:36:41 GMT 2025` Edited by `admin` on `Wed Apr 02 03:36:41 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependovirus
Organism Species	adeno-associated virus
Author	NONE
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	AAV2/8.CB7.CI.AMD42.RBG
Part	whole
Record UNII	GJI4EV4B3C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Surabgene Lomparvovec

Official Name

English

DNA (recombinant replication-defective adeno-associated virus 8 vector RGX-314 cytomegalovirus immediate-early enhancer element plus chicken ?-actin gene promoter plus chicken ?-actin gene intron plus human-Mus musculus anti-(human vascular endothelial g

Preferred Name

English

surabgene lomparvovec [INN]

Common Name

English

recombinant, non-replicating adeno-associated virus serotype 8 (rAAV8) vector encoding a soluble humanised anti-vascular endothelial growth factor (VEGF) antibody fragment (Fab) under control of a hybrid cytomegalovirus (CMV) immediate-early enhancer/chi

Common Name

English

Code System Code Type Description

CLINICAL_TRIALS.GOV

NCT03066258