Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C24H28Cl2N4O3 |
| Molecular Weight | 491.41 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1C=C(Cl)C=C[C@@H]1[C@@]3(CN2C=CN=C2)OC[C@H](COC4=CC=C(C=C4)N5CCNCC5)O3
InChI
InChIKey=LVJVPTCFRIHTGD-UBEQRZCFSA-N
InChI=1S/C24H28Cl2N4O3/c25-18-1-6-22(23(26)13-18)24(16-29-10-7-28-17-29)32-15-21(33-24)14-31-20-4-2-19(3-5-20)30-11-8-27-9-12-30/h1-7,10,13,17,21-23,27H,8-9,11-12,14-16H2/t21-,22?,23?,24-/m0/s1
| Molecular Formula | C24H28Cl2N4O3 |
| Molecular Weight | 491.41 |
| Charge | 0 |
| Count |
|
| Stereochemistry | MIXED |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 13:48:30 GMT 2023
by
admin
on
Sat Dec 16 13:48:30 GMT 2023
|
| Record UNII |
GJA4GNA6QM
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
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Common Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
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156596531
Created by
admin on Sat Dec 16 13:48:30 GMT 2023 , Edited by admin on Sat Dec 16 13:48:30 GMT 2023
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PRIMARY | |||
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133345-18-3
Created by
admin on Sat Dec 16 13:48:30 GMT 2023 , Edited by admin on Sat Dec 16 13:48:30 GMT 2023
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PRIMARY | |||
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GJA4GNA6QM
Created by
admin on Sat Dec 16 13:48:30 GMT 2023 , Edited by admin on Sat Dec 16 13:48:30 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE INACTIVE |
Evidence that CYP3A4 plays a significant role in metabolism of ketoconazole is that co-administration of CYP3A4 inducers, such as phenytoin, carbamazepine, and rifampin, can cause as much as a 50% reduction in levels of ketoconazole.
MAY BE CLINICALLY SIGNIFICANT
|
