U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 01:42:56 GMT 2025
Edited
by admin
on Wed Apr 02 01:42:56 GMT 2025
Source Materials Class ORGANISM
Source Materials Type FUNGUS
Source Materials State KILLED
Organism Family Saccharomycetaceae
Organism Genus Saccharomyces
Organism Species cerevisiae
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name GI-4020 (RAS-G12R, Q61H, Q61L)
Part whole
Record UNII
GI9GH3JYD1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GI-4000 component GI-4020
Preferred Name English
GI-4020
Code English
Heat-inactivated Saccharomyces cerevisiae yeast expressing KRAS G12R, KRAS Q61L, KRAS Q61H
Common Name English
Code System Code Type Description
FDA UNII
GI9GH3JYD1
Created by admin on Wed Apr 02 01:42:56 GMT 2025 , Edited by admin on Wed Apr 02 01:42:56 GMT 2025
PRIMARY
CAS
1521298-08-7
Created by admin on Wed Apr 02 01:42:56 GMT 2025 , Edited by admin on Wed Apr 02 01:42:56 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY
immunotherapeutics target the RAS oncoprotein (RAS-G12R, Q61H, Q61L)

Physical Modifications

Modification Role Parameter Name Amount
Inactivation HEAT

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
VECTOR EXPRESSED PROTEIN UNSPECIFIED SUBSTANCE
8371610f
(not in database)