U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:40:10 GMT 2023
Edited
by admin
on Sat Dec 16 13:40:10 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
GG0AN49Y59
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
QUAVONLIMAB
INN   USAN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4) (HUMAN-MUS MUSCULUS MONOCLONAL M3 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL M3 .KAPPA.-CHAIN, DIMER
Common Name English
quavonlimab [INN]
Common Name English
QUAVONLIMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), HUMANIZED MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HUMANIZED (1-445) (VH (HOMO SAPIENS IGHV3-72*01 (84.7%)-(IGHD)-IGHJ4*01 (92.9%)) CDR-IMGT (8.10.6)
Common Name English
Quavonlimab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), HUMANIZED MONOCLONAL ANTIBODY
Common Name English
MK-1308A COMPONENT QUAVONLIMAB
Code English
Code System Code Type Description
CLINICAL_TRIALS.GOV
NCT03179436
Created by admin on Sat Dec 16 13:40:10 GMT 2023 , Edited by admin on Sat Dec 16 13:40:10 GMT 2023
PRIMARY
FDA UNII
GG0AN49Y59
Created by admin on Sat Dec 16 13:40:10 GMT 2023 , Edited by admin on Sat Dec 16 13:40:10 GMT 2023
PRIMARY
NCI_THESAURUS
C150679
Created by admin on Sat Dec 16 13:40:10 GMT 2023 , Edited by admin on Sat Dec 16 13:40:10 GMT 2023
PRIMARY
USAN
JK-70
Created by admin on Sat Dec 16 13:40:10 GMT 2023 , Edited by admin on Sat Dec 16 13:40:10 GMT 2023
PRIMARY
INN
11234
Created by admin on Sat Dec 16 13:40:10 GMT 2023 , Edited by admin on Sat Dec 16 13:40:10 GMT 2023
PRIMARY
CAS
2254059-25-9
Created by admin on Sat Dec 16 13:40:10 GMT 2023 , Edited by admin on Sat Dec 16 13:40:10 GMT 2023
PRIMARY
From To
1_22 1_98
1_142 1_198
1_218 3_214
1_224 2_224
1_227 2_227
1_259 1_319
1_365 1_423
2_22 2_98
2_142 2_198
2_218 4_214
2_259 2_319
2_365 2_423
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL