ANAPLASTIC LYMPHOMA KINASE L1152R

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:57:16 GMT 2025` Edited by `admin` on `Wed Apr 02 00:57:16 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type	TYROSINE KINASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	GE1G5FR3D2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CD-246 L1152R

Preferred Name

English

ANAPLASTIC LYMPHOMA KINASE L1152R

Common Name

English

ALK L1152R MUTANT

Common Name

English

ALK TYROSINE KINASE RECEPTOR L1152R

Systematic Name

English

CD246 L1152R

Code

English

Code System Code Type Description

EC (ENZYME CLASS)

EC 2.7.10.1

Created by admin on Wed Apr 02 00:57:16 GMT 2025 , Edited by admin on Wed Apr 02 00:57:16 GMT 2025

PRIMARY

UNIPROT

Q9UM73

Created by admin on Wed Apr 02 00:57:16 GMT 2025 , Edited by admin on Wed Apr 02 00:57:16 GMT 2025

PRIMARY

WIKIPEDIA

ANAPLASTIC LYMPHOMA KINASE

Created by admin on Wed Apr 02 00:57:16 GMT 2025 , Edited by admin on Wed Apr 02 00:57:16 GMT 2025

PRIMARY

FDA UNII

GE1G5FR3D2

Created by admin on Wed Apr 02 00:57:16 GMT 2025 , Edited by admin on Wed Apr 02 00:57:16 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_151
N	1_226
N	1_267
N	1_306
N	1_393
N	1_406
N	1_427
N	1_545
N	1_553
N	1_609
N	1_691
N	1_790
N	1_845
N	1_846
N	1_868
N	1_968

Related Record Type Details


					OSP71S83EU

LORLATINIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1060] [1_1074] [1_1078] [1_1113] [1_1260] [1_1489] [1_1586]				TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL